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Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. It functions by inhibiting cyclooxygenase (COX) enzymes, leading to a decrease in prostaglandin synthesis, which mediates inflammation and pain. Etodolac is a monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active. It has a role as a non-steroidal anti-inflammatory drug, a cyclooxygenase 2 inhibitor, a non-narcotic analgesic and an antipyretic. It is a monocarboxylic acid and an organic heterotricyclic compound. It's other identifier is UNII: 2M36281008.
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. It functions by inhibiting cyclooxygenase (COX) enzymes, leading to a decrease in prostaglandin synthesis, which mediates inflammation and pain. Etodolac is a monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is ...
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Active Pharmaceutical Ingredients (APIs)
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Chemical Properties & Specifications
Acute Toxicity (Oral): Category 3 Eye Irritation: Category 2A Reproductive Toxicity: Category 2
H301: Toxic if swallowed. H319: Causes serious eye irritation. H361: Suspected of damaging fertility or the unborn child.
P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P264: Wash hands thoroughly after handling. P270: Do not eat, drink, or smoke when using this product. P280: Wear protective gloves, clothing, and eye protection. P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. P308+P313: IF exposed or concerned: Get medical advice/attention. P405: Store locked up. P501: Dispose of contents/container in accordance with local/regional/national/international regulations.
Used in the formulation of medications for the treatment of osteoarthritis, rheumatoid arthritis, and acute pain management.
Acts as an anti-inflammatory and analgesic agent in various pharmaceutical formulations
Store at refrigerated temperatures between 0–10°C.
Keep in a cool, dry place away from direct sunlight and moisture.
Store in tightly sealed, light-resistant containers to prevent degradation.
Available in 5 g, 25 g, and bulk quantities.
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) prescribed to alleviate pain and reduce inflammation associated with conditions such as osteoarthritis and rheumatoid arthritis.
It functions by inhibiting cyclooxygenase (COX) enzymes, leading to decreased prostaglandin synthesis, which in turn reduces inflammation and pain.
Common side effects may include gastrointestinal discomfort, dizziness, headache, and edema.
It may pose risks to the fetus. Etodolac is suspected of damaging fertility or the unborn child and should be used during pregnancy only if clearly needed and prescribed by a healthcare provider.
It's essential to consult a healthcare provider before combining Etodolac with other medications, as potential interactions may occur.
