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Ethynylmagnesium Bromide (CAS 4301-14-8) serves as a vital alkynyl Grignard reagent in the API intermediates market, primarily utilized for the nucleophilic ethynylation of chiral aldehydes and ketones to produce propargylic alcohols with a mandatory Pharma/API purity of 99%. Ethynylbromomagnesium is increasingly integrated into domestic custom synthesis services as U.S. based CDMOs prioritize high purity fine chemicals to ensure supply chain resilience and meet stringent FDA regulatory compliance standards for complex natural product total synthesis. Bromo(ethynyl)magnesium has become a fundamental tool for any specialized bulk chemical supplier in the United States, facilitating advanced cross-coupling and click chemistry applications in material science and pharmaceutical manufacturing where a General Industry purity of 98% is maintained for large-scale industrial productions. We are an established Ethynylmagnesium Bromide intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting Ethynylmagnesium Bromide COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities
Ethynylmagnesium Bromide (CAS 4301-14-8) serves as a vital alkynyl Grignard reagent in the API intermediates market, primarily utilized for the nucleophilic ethynylation of chiral aldehydes and ketones to produce propargylic alcohols with a mandatory Pharma/API purity of 99%. Ethynylbromomagnesium is increasingly integrated into domestic custom synthesis services as U.S. based CDMOs prioritize high purity fine chemicals to ensure supply chain resilience and meet stringent FDA regulatory compliance standards for complex natural product total synthesis. Bromo(ethynyl)magnesium has become a fundamental tool for any specialized bulk chemical supplier in the United States, facilitating advanced c...
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
A cornerstone Grignard reagent used as a potent nucleophile for the introduction of ethynyl groups into various molecular scaffolds through 1,2-addition to aldehydes and ketones
A vital building block employed in the ethynylation of chiral aldehydes and the total synthesis of complex natural products like the antibiotic (+)-4-demethoxydaunomycin
A specialized reagent used to prepare alkyl(triethynyl)germanes and functionalized polymers for the development of materials with specific electronic or optical properties
A versatile intermediate used in the synthesis of ethynyl aziridines, unsaturated phosphonites, and anthracene-containing species for advanced organic frameworks.
Ethynylmagnesium Bromide is a highly reactive organometallic Grignard reagent primarily used in organic synthesis for carbon-carbon bond formation and the introduction of ethynyl groups into various molecular scaffolds
This compound is widely utilized in the pharmaceutical, agrochemical, material science, and chemical manufacturing industries for the production of complex organic molecules, natural products, and polymers
It is commonly supplied and used as a solution in anhydrous solvents such as tetrahydrofuran (THF) or diethyl ether and must be handled under inert atmospheres
Standard specifications include CAS number 4301-14-8, molar mass 129.24 g/mol, and availability of documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a generally accepted MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
