Domperidone Maleate is a selective dopamine D2 receptor antagonist used in treating gastrointestinal motility disorders and nausea. Unlike centrally acting agents, it does not significantly cross the blood–brain barrier, making it preferred in patients sensitive to extrapyramidal side effects. It’s formulated as an API in solid oral dosage forms and suspensions. Stable Salt Form: Maleate version is preferred for improved solubility and oral bioavailability.
Domperidone Maleate is a selective dopamine D2 receptor antagonist used in treating gastrointestinal motility disorders and nausea. Unlike centrally acting agents, it does not significantly cross the blood–brain barrier, making it preferred in patients sensitive to extrapyramidal side effects. It’s formulated as an API in solid oral dosage forms and suspensions. Stable Salt Form: Maleate version is preferred for improved solubility and oral bioavailability.
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Active Pharmaceutical Ingredients (APIs)
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Chemical Properties & Specifications
Used in the treatment of delayed gastric emptying, GERD, and functional dyspepsia.
Indicated for prevention and treatment of nausea and vomiting caused by gastrointestinal disorders or chemotherapy.
Sometimes used off-label to increase prolactin levels for postpartum lactation support.
The assay is typically not less than 98 percent determined by HPLC under validated conditions
High Performance Liquid Chromatography is the standard method used for assay and related substances
EP/BP/USP/IP Compliant API, GMP-Grade & DMF Available, Micronized and non-micronized forms
MOQ starts at one kilogram and can be scaled based on formulation or bulk needs
Only active pharmaceutical ingredient is offered, but partnerships for finished formulation development can be recommended
Manufacturing sites are GMP certified with options for WHO-GMP, CEP support, and DMF filing based on customer needs
Yes, the product is offered in both Domperidone base and Domperidone maleate; maleate is preferred for oral formulations
Pharmacopoeial grades such as IP, BP, and USP are available with proper analytical support and batch consistency
API standards, analytical method development, QC applications
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