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Dimethylacetamide (CAS 127-19-5) serves as a high-performance dipolar aprotic solvent essential for the production of spandex fibers and high-strength polyimide films, where American bulk chemical supplier networks are prioritizing high-purity grades to meet the rigorous demands of the domestic aerospace and textile industries. N,N-Dimethylacetamide has seen a significant uptick in demand within the United States pharmaceutical sector as a preferred medium for custom synthesis services, particularly in the crystallization of antibiotics and as an excipient in specialized injectable formulations that require stringent adherence to evolving FDA quality standards. DMAC is increasingly critical for the domestic manufacturing of semi-permeable membranes used in advanced water purification and hemodialysis, driving a shift toward localized sourcing of high purity fine chemicals to mitigate global logistics risks and ensure compliance with EPA TSCA environmental regulations. As an established Dimethylacetamide supplier with Dimethylacetamide >= 99% purity in the united states of america, we ensure dependable supply, consistent quality, and complete regulatory documentation, including Dimethylacetamide CoA and TDS across all grades. Beyond supply, we support partners through the entire product lifecycle from route scouting, process and formulation development, and analytical method development to scale-up, process optimisation, and pilot-to-commercial manufacturing. Our teams also assist with GMP-compliant quality assurance, regulatory documentation, and nationwide supply chain capabilities and logsitics coordination on all the 50 united states.
Dimethylacetamide (CAS 127-19-5) serves as a high-performance dipolar aprotic solvent essential for the production of spandex fibers and high-strength polyimide films, where American bulk chemical supplier networks are prioritizing high-purity grades to meet the rigorous demands of the domestic aerospace and textile industries. N,N-Dimethylacetamide has seen a significant uptick in demand within the United States pharmaceutical sector as a preferred medium for custom synthesis services, particularly in the crystallization of antibiotics and as an excipient in specialized injectable formulations that require stringent adherence to evolving FDA quality standards. DMAC is increasingly critical ...
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Pharmaceutical
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Excipients
Solvents & Solubilizers
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Chemical Properties & Specifications
Acute Tox. 4 (99.4%)
Eye Irrit. 2 (35.5%)
Acute Tox. 4 (96.5%)
Repr. 1B (91.5%) & Repr. 1B (14.1%)
P203, P261, P271, P280, P302+P352, P304+P340, P317, P318, P321, P362+P364, P405, and P501
Solvent in wet and dry spinning of Spandex (Elastane), polyacrylonitrile (acrylic) fibers, polyimides, and heavy-duty aramid fibers
Efficient reaction medium for synthesising advanced antibiotics (like cephalosporins) and anti-tumour medications because it enhances reaction rates (FDA-approved drug excipient & vehicle in specialized intravenous treatments)
Crucial in casting porous dialyzer membranes used for medical hemodialysis
High-purity cleaning solvent and stripper during the manufacturing of semiconductors and photoresists
A versatile, high-boiling polar aprotic solvent widely used in the production of fibers such as polyacrylonitrile and spandex, as well as in the adhesive industry
A common reaction medium employed in the synthesis of pharmaceuticals, plasticizers, and complex organic compounds due to its stability with strong bases
A specialized component of solvent mixtures, often with lithium chloride, used to create true molecular dispersions of cellulose for fiber preparation and gel permeation chromatography
A high-purity solvent suitable for peptide coupling and solid-phase synthesis applications
A certified reference material and secondary standard utilized in HPLC, headspace gas chromatography, and spectrophotometric analysis.
Our product is a premium-grade N,N-Dimethylacetamide (DMAc), structurally classified as a heavy-duty aliphatic amide and registered globally under CAS Number 127-19-5.
DMAc features an exceptionally high dipole moment and superior high-boiling solvency power. Unlike standard solvents, it functions as an intricate reaction medium and polymer solubilizer capable of dissolving tough, high-molecular-weight polymers.
We utilise precision chemical synthesis combined with rigorous fractional distillation. This process ensures a consistent, ultra-pure assay and absolute clarity in liquid matrices, maintaining a strict refractive index standardisation across all batches.
The product maintains a robust vapour pressure profile with an optimised volatility rate. It offers exceptional thermal resistance and acts as a structural anchor during high-heat processing, featuring an outstanding boiling point exceeding 165°C.
Every bulk contract order is backed by complete regulatory compliance documentation, including a Dimethylacetamide (CoA & SDS), and REACH certification, alongside tiered container-load discounts and international logistics coordination.
Dimethylacetamide, also known as DMAc or DMA, is a colorless, high-boiling, polar aprotic solvent used extensively in organic synthesis and as a reaction medium for producing fibers like polyacrylonitrile and spandex
This compound is widely utilized in the textile, pharmaceutical, polymer, agrochemical, and electronics industries for fiber spinning, drug synthesis, and film production
It is a water-miscible liquid that is compatible with most organic solvents, including ethers, esters, ketones, and aromatic compounds, and is stable in the presence of strong bases
Standard specifications include CAS number 127-19-5, purity levels typically ≥99.9%, a boiling point of 164-166°C, and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Active Pharmaceutical Ingredients (APIs)
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