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Diethyl (p-Toluenesulfonyloxymethyl)phosphonate (CAS 31618-90-3) is an indispensable building block in the high purity fine chemicals sector, where it is primarily utilized for the synthesis of Tenofovir and Adefovir, requiring a Pharma/API purity of 99% to ensure the efficacy of antiretroviral therapies. Diethyl (tosyloxy)methylphosphonate has seen a surge in demand within the United States API intermediates market as domestic manufacturers prioritize supply chain resilience and move away from volatile global sourcing to secure reliable, high-performance reagents. DESMP is increasingly integrated into custom synthesis services offered by North American CDMOs who focus on stringent regulatory compliance and advanced analytical validation to support the rapid scale-up of semi-finished formulations. We are an established Diethyl (p-toluenesulfonyloxymethyl)phosphonate (DESMP) intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting Diethyl (p-toluenesulfonyloxymethyl)phosphonate (DESMP) COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities
Diethyl (p-Toluenesulfonyloxymethyl)phosphonate (CAS 31618-90-3) is an indispensable building block in the high purity fine chemicals sector, where it is primarily utilized for the synthesis of Tenofovir and Adefovir, requiring a Pharma/API purity of 99% to ensure the efficacy of antiretroviral therapies. Diethyl (tosyloxy)methylphosphonate has seen a surge in demand within the United States API intermediates market as domestic manufacturers prioritize supply chain resilience and move away from volatile global sourcing to secure reliable, high-performance reagents. DESMP is increasingly integrated into custom synthesis services offered by North American CDMOs who focus on stringent regulator...
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
P264, P280, P302+P352, P305+P351+P338, P332+P313, P337+P313, and P362
Skin Irrit. 2 (100%)
Eye Irrit. 2 (100%)
Diethyl p-toluene sulfonyl oxymethyl phosphonate (DESMP) is primarily utilized as a critical intermediate in the synthesis of anti-retroviral and nucleoside antiviral drugs, specifically for the production of Tenofovir and Adefovir used in the treatment of HIV, Hepatitis B (HBV), and Cytomegalovirus (CMV)
The compound serves as a valuable phosphorylating agent and building block in the development of phosphine ligands, herbicides, and fungicides within the agrochemical and fine chemical industries
It is employed in laboratory research and development for the synthesis of acyclic nucleoside phosphonates and other bioactive molecules to investigate viral replication inhibition.
Diethyl p-toluene sulfonyl oxymethyl phosphonate, commonly known as DESMP, is a synthetic intermediate and phosphorylating agent primarily used in the synthesis of nucleoside antiviral drugs like Tenofovir and Adefovir, as well as in the production of herbicides and fungicides
This chemical is widely utilized in the pharmaceutical, agrochemical, and biotechnology industries for drug development and pesticide manufacturing
It is compatible with various organic solvents such as dichloromethane, ethyl acetate, and methanol, and is typically used in liquid-phase chemical synthesis
Standard specifications include CAS number 31618-90-3, high purity (typically ≥97% or ≥98.5%), and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and mode of transport.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
Description : P-Nitrobenzoyl Chloride (CAS 122-04-3) is a critical building block in the API intermediates market,...
