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Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate (CAS NO : 42771-81-3)

Diethyl 2-(2-fluoro-[1,1'-biphenyl]-4-yl)-2-methylmalonate (CAS 42771-81-3) is a critical high purity fine chemical increasingly sought by North American CDMOs for the complex synthesis of fluorinated API intermediates, where a Pharma/API purity 99% is mandatory to ensure the metabolic stability and potency of next-generation bioactive molecules. 1,3-Diethyl 2-(2-fluoro-4-phenylphenyl)-2-methylpropanedioate serves as a specialized building block in the burgeoning US custom synthesis services sector, providing the essential biphenyl-fluorine scaffold required for advanced anti-inflammatory and cardiovascular drug candidates amid a strategic global sourcing shift toward domestic supply chain reliability. Diethyl 2-(2-fluorobiphenyl-4-yl)-2-methylmalonate remains a high-value asset for the American API intermediates market, with General Industry purity 98% variants supporting large-scale agrochemical research and specialty polymer development, reinforcing the need for a domestic bulk chemical supplier capable of navigating stringent EPA and FDA regulatory landscapes. We are an established Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities

Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate

Diethyl 2-(2-fluoro-[1,1'-biphenyl]-4-yl)-2-methylmalonate (CAS 42771-81-3) is a critical high purity fine chemical increasingly sought by North American CDMOs for the complex synthesis of fluorinated API intermediates, where a Pharma/API purity 99% is mandatory to ensure the metabolic stability and potency of next-generation bioactive molecules. 1,3-Diethyl 2-(2-fluoro-4-phenylphenyl)-2-methylpropanedioate serves as a specialized building block in the burgeoning US custom synthesis services sector, providing the essential biphenyl-fluorine scaffold required for advanced anti-inflammatory and cardiovascular drug candidates amid a strategic global sourcing shift toward domestic supply chain r...

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Pharmaceutical Actives & Precursors

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Intermediates & Precursors

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Chemical Properties & Specifications

Applications of Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate

Pharmaceutical Intermediate

An important building block utilized in the synthesis of the nonsteroidal anti-inflammatory drug (NSAID) flurbiprofen

Analytical Reference Standard

A fully characterized chemical compound used for analytical method development, method validation (AMV), and quality control (QC) applications to ensure the quality and traceability of flurbiprofen according to pharmacopeial standards

Organic Synthesis Building Block

A functionalized malonate derivative used in academic and industrial research for the development of complex molecules and medicinal compounds.

Have Questions About Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate?
We've Got Answers.

Diethyl-2-(2-Fluoro-4-biphenyl)-2-methyl malonate, also known by CAS 42771-81-3, is a fully characterized chemical compound used as a reference standard for the API Flurbiprofen. It is utilized for analytical method development, validation, and quality control applications during the synthesis and formulation stages of drug development

This compound is primarily used in the pharmaceutical and analytical research industries as a reference standard and impurity for quality control in the production of nonsteroidal anti-inflammatory drugs

It is soluble in chloroform and methanol and is typically handled as a syrup or liquid for use in analytical laboratory settings

Standard specifications include CAS number 42771-81-3, molecular formula C20H21FO4, and documentation such as COA, TDS, impurity reports, and regulatory compliance documents

Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time

The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.

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