

Bis(4-nitrophenyl) carbonate (CAS 5070-13-3) serves as a critical, high-purity carbonylating agent and safer solid alternative to phosgene in peptide synthesis and bioconjugation workflows, making it highly valuable for custom synthesis services supporting the expanding domestic CDMO footprint in the United States. Carbonic acid, bis(4-nitrophenyl) ester has seen increased traction across leading marketplaces in the United States as pharmaceutical manufacturers prioritize high purity fine chemicals to mitigate global sourcing risks and enhance supply chain resilience for critical therapeutic pipelines. 4,4'-Dinitrodiphenyl carbonate is increasingly utilized as a versatile coupling agent for the preparation of activated p-nitrophenyl esters and carbamate-linked systems, aligning with recent trends toward robust regulatory compliance and stringent quality control standards required by the American Chemical Society and domestic bulk chemical supplier networks. We are an established Bis(4-nitrophenyl) carbonate intermediates supplier with Bis(4-nitrophenyl) carbonate >= 99% purity in the american region, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting Bis(4-nitrophenyl) carbonate COA/TDS/SDS region-specific regulatory support, reliable lead times, united states nationwide supply chain capabilities


Bis(4-nitrophenyl) carbonate (CAS 5070-13-3) serves as a critical, high-purity carbonylating agent and safer solid alternative to phosgene in peptide synthesis and bioconjugation workflows, making it highly valuable for custom synthesis services supporting the expanding domestic CDMO footprint in the United States. Carbonic acid, bis(4-nitrophenyl) ester has seen increased traction across leading marketplaces in the United States as pharmaceutical manufacturers prioritize high purity fine chemicals to mitigate global sourcing risks and enhance supply chain resilience for critical therapeutic pipelines. 4,4'-Dinitrodiphenyl carbonate is increasingly utilized as a versatile coupling agent for ...
Pharmaceutical
Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364
Skin Irrit. 2 (100%)
Eye Irrit. 2 (100%)
A coupling reagent used for the preparation of activated 4-nitrophenyl esters of N-protected amino acids
A stable, solid alternative to phosgene utilized for the synthesis of symmetrical and unsymmetrical ureas, carbamates, and carbonates
A versatile reagent used to link biomolecules to proteins and other carriers in drug delivery research
A functional building block for the synthesis of various pharmaceutical intermediates, agrochemicals, and high-performance polymers.
Bis(4-nitrophenyl) carbonate is a versatile organic compound used as a safer alternative to phosgene for carbonylation, acting as a reagent for the synthesis of carbonates, ureas, carbamates, and peptide coupling
This compound is widely utilized in the pharmaceutical, agrochemical, polymer chemistry, and materials science industries for drug development and the production of advanced materials
It is soluble in organic solvents such as chloroform, tetrahydrofuran, acetone, and dichloromethane, and is typically used in organic synthesis and liquid-phase protocols
Standard specifications include CAS number 5070-13-3, high purity (typically >98%), and availability of documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Active Pharmaceutical Ingredients (APIs)
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