Bis(2-diphenylphosphinophenyl)ether

CAS Number: 166330-10-5

Molecular Formula: C36H28OP2

About Bis(2-diphenylphosphinophenyl)ether

DPEphos (CAS 166330-10-5) is increasingly recognized by US-based CDMOs as a premier bidentate phosphine ligand, specializing in high-efficiency homogeneous catalysis for Suzuki-Miyaura and Buchwald-Hartwig couplings to streamline the synthesis of complex oncology-related molecules. Bis(2-diphenylphosphinophenyl)ether h...

Bis(2-diphenylphosphinophenyl)ether Specifications

CAS Number

166330-10-5

Molecular Formula

C36H28OP2

Molecular Weight

538.57 g/mol

IUPAC Name

[2-(2-diphenylphosphanylphenoxy)phenyl]-diphenylphosphane

Canonical SMILES

C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=CC=CC=C3OC4=CC=CC=C4P(C5=CC=CC=C5)C6=CC=CC=C6

InChI Key

RYXZOQOZERSHHQ-UHFFFAOYSA-N

CAS Number

166330-10-5

Molecular Formula

C36H28OP2

Molecular Weight

538.57 g/mol

IUPAC Name

[2-(2-diphenylphosphanylphenoxy)phenyl]-diphenylphosphane

Canonical SMILES

C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=CC=CC=C3OC4=CC=CC=C4P(C5=CC=CC=C5)C6=CC=CC=C6

InChI Key

RYXZOQOZERSHHQ-UHFFFAOYSA-N

Molecular Weight

538.57 g/mol

Physical appearance

White to almost white powder to crystal

Catalytic Ligand

A versatile bidentate phosphine ligand primarily used in transition metal-catalyzed reactions, such as Suzuki-Miyaura coupling, Buchwald-Hartwig amination, and Heck reactions, to enhance efficiency and selectivity in organic synthesis

Pharmaceutical Intermediate

A crucial building block utilized in the synthesis of complex active pharmaceutical ingredients and therapeutic molecules, including those used in oncology

Materials Science Additive

A functional component employed in the development of advanced materials, such as conductive polymers and organic electronic materials, to tailor molecular properties

Green Chemistry Enabler

A specialized ligand used in borrowing hydrogen methodologies and other sustainable synthetic routes to reduce waste and energy consumption in chemical manufacturing.