

Benzyl (S,S,S)-2-azabicyclo[3.3.0]octane-3-carboxylate hydrochloride (CAS No: 87269-87-2) is a critical chiral building block extensively utilized by North American pharmaceutical manufacturers for the asymmetric synthesis of Ramipril, where precise (S,S,S) stereochemistry is vital to the therapeutic efficacy of the final ACE inhibitor. As the prevalence of hypertension and cardiovascular conditions continues to rise across the united states region, domestic API producers require a steady, high-volume supply of this bicyclic heterocyclic precursor, driving the shift toward advanced process chemistry and sustainable synthesis methods to maximize yields and atom economy. With the FDA and other regulatory bodies intensifying oversight on isomeric purity and genotoxic impurities, U.S. procurement teams are increasingly prioritizing suppliers who provide comprehensive analytical dossiers and maintain rigorous quality management systems within the pharmaceutical supply chain. As an established global supplier of Benzyl (S,S,S)-2-azabicyclo octane-3-carboxylate hydrochloride with >= 99% purity, we ensure minimal impurity carry-over in final API production and offer a diverse portfolio of pharmaceutical intermediates for manufacturers and formulators. We provide full analytical support, including HPLC, NMR, and MS data, along with region-specific regulatory documentation such as CoA, TDS, and SDS. Our commitment to the U.S. market includes reliable lead times, technical expertise in scale-up and process optimization, and robust logistics capabilities to support nationwide distribution across all 50 states.

Benzyl (S,S,S)-2-azabicyclo[3.3.0]octane-3-carboxylate hydrochloride (CAS No: 87269-87-2) is a critical chiral building block extensively utilized by North American pharmaceutical manufacturers for the asymmetric synthesis of Ramipril, where precise (S,S,S) stereochemistry is vital to the therapeutic efficacy of the final ACE inhibitor. As the prevalence of hypertension and cardiovascular conditions continues to rise across the united states region, domestic API producers require a steady, high-volume supply of this bicyclic heterocyclic precursor, driving the shift toward advanced process chemistry and sustainable synthesis methods to maximize yields and atom economy. With the FDA and other...
Pharmaceutical
Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
P203, P261, P264, P270, P272, P280, P301+P316, P302+P352, P318, P321, P330, P333+P317, P362+P364, P405, and P501
Acute Tox. 3 (100%)
Skin Sens. 1 (100%)
An intermediate used in the preparation of ramipril, an angiotensin-converting enzyme (ACE) inhibitor
A starting material for the synthesis of octahydrocyclopenta[b]pyrrole-2-carbonitrile derivatives as potent DPP4 inhibitors
A reference material for Abbreviated New Drug Applications (ANDA) and New Drug Applications (NDA) in the commercial manufacturing of Ramipril
A chiral building block used in asymmetric synthesis and medicinal chemistry for the design of enzyme inhibitors and bioactive molecules
Benzyl (S,S,S)-2-azabicyclo octane-3-carboxylate hydrochloride is a chiral bicyclic amino acid ester derivative with the molecular formula C15H19NO2·HCl, primarily used as a key pharmaceutical intermediate in the synthesis of ramipril, an angiotensin-converting enzyme (ACE) inhibitor, and other bioactive molecules like DPP4 inhibitors
This compound is heavily utilized in the pharmaceutical industry, specifically within medicinal chemistry, asymmetric organic synthesis, and commercial API manufacturing
It is primarily compatible with organic synthesis protocols, showing moderate solubility in polar organic solvents like methanol and dimethyl sulfoxide, and poor solubility in water
Standard specifications include CAS number 87269-87-2, a molecular weight of 281.78 g/mol, a purity typically ≥98.0% by HPLC, and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Active Pharmaceutical Ingredients (APIs)
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