Benzyl (S,S,S)-2-azabicyclo octane-3-carboxylate hydrochloride

Benzyl (S,S,S)-2-azabicyclo octane-3-carboxylate hydrochloride

CAS Number
87269-87-2
Molecular Formula
C15H20ClNO2
Purity
99% Benzyl (S,S,S)-2-azabicyclo octane-3-carboxylate hydrochloride

About Benzyl (S,S,S)-2-azabicyclo octane-3-carboxylate hydrochloride

Benzyl (S,S,S)-2-azabicyclo[3.3.0]octane-3-carboxylate hydrochloride (CAS No: 87269-87-2) is a critical chiral building block extensively utilized by North American pharmaceutical manufacturers for the asymmetric synthesis of Ramipril, where precise (S,S,S) stereochemistry is vital to the therapeutic efficacy of the fi...

Benzyl (S,S,S)-2-azabicyclo octane-3-carboxylate hydrochloride Specifications

CAS Number
87269-87-2
Molecular Formula
C15H20ClNO2
Molecular Weight
281.78 g/mol
IUPAC Name
benzyl (2S,3aS,6aS)-1,2,3,3a,4,5,6,6a-octahydrocyclopenta[b]pyrrole-2-carboxylate;hydrochloride
Canonical SMILES
Cl[H].[H][C@@]12CCC[C@]1([H])N[C@@H](C2)C(=O)OCc3ccccc3
InChI Key
HLXCXOQXUDRJLF-JKBZPBJLSA-N
InChI
InChI=1S/C15H19NO2.ClH/c17-15(18-10-11-5-2-1-3-6-11)14-9-12-7-4-8-13(12)16-14;/h1-3,5-6,12-14,16H,4,7-10H2;1H/t12-,13-,14-;/m0./s1
MDL Number
MFCD04974076
HSN No
29189990
Molecular Weight
281.78 g/mol
Purity
99% Benzyl (S,S,S)-2-azabicyclo octane-3-carboxylate hydrochloride
Physical appearance
White to off-white crystalline solid
odor
No strong characteristic odor
Melting Point
176-180 °C (lit.)
Boiling Point
390.5°C at 760 mmHg
Density
1.57 g/cm3
Precise Quality
≥98.0%
PSA
38.3 Ų
Precautionary Statement Codes
P203, P261, P264, P270, P272, P280, P301+P316, P302+P352, P318, P321, P330, P333+P317, P362+P364, P405, and P501
Hazard Classes and Categories
Acute Tox. 3 (100%) Skin Sens. 1 (100%)

Synthetic Intermediate

An intermediate used in the preparation of ramipril, an angiotensin-converting enzyme (ACE) inhibitor

Starting Material

A starting material for the synthesis of octahydrocyclopenta[b]pyrrole-2-carbonitrile derivatives as potent DPP4 inhibitors

Reference Material

A reference material for Abbreviated New Drug Applications (ANDA) and New Drug Applications (NDA) in the commercial manufacturing of Ramipril

Building Block

A chiral building block used in asymmetric synthesis and medicinal chemistry for the design of enzyme inhibitors and bioactive molecules

Benzyl (S,S,S)-2-azabicyclo octane-3-carboxylate hydrochloride FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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