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Benzyl chloroformate (50% in toluene)

Benzyl chloroformate (50% in toluene)

CAS Number: 501-53-1

Molecular Formula: C8H7ClO2

About Benzyl chloroformate (50% in toluene)

Benzyl chloroformate (CAS 501-53-1) is a critical reagent in the United States pharmaceutical sector, primarily utilized for the introduction of the benzyloxycarbonyl (Cbz) protecting group in complex peptide synthesis and the manufacturing of high-purity fine chemicals. Phenylmethyl carbonochloridate serves as an esse...

Benzyl chloroformate (50% in toluene) Specifications

CAS Number

501-53-1

Molecular Formula

C8H7ClO2

Molecular Weight

170.59 g/mol

IUPAC Name

Benzyl carbonochloridate

Canonical SMILES

C1=CC=C(C=C1)COC(=O)Cl

InChI Key

HSDAJNMJOMSNEV-UHFFFAOYSA-N

PubChem CID

10387

CAS Number

501-53-1

Molecular Formula

C8H7ClO2

Molecular Weight

170.59 g/mol

IUPAC Name

Benzyl carbonochloridate

Canonical SMILES

C1=CC=C(C=C1)COC(=O)Cl

InChI Key

HSDAJNMJOMSNEV-UHFFFAOYSA-N

PubChem CID

10387

Molecular Weight

170.59 g/mol

Physical appearance

Colorless to light yellow clear liquid

Organic Synthesis Reagent

A versatile reagent extensively used for the introduction of the benzyloxycarbonyl (Cbz or Z) protecting group for amines and alcohols in complex multi-step organic synthesis

Pharmaceutical Intermediate

A critical building block employed in the synthesis of various medicinal compounds, antibiotics, and active pharmaceutical ingredients

Peptide Synthesis Protecting Agent

An essential reagent used to protect the amine functionality of amino acids, ensuring selective peptide bond formation in the assembly of peptides and proteins

Agrochemical Intermediate

A key chemical intermediate used in the development and production of pesticides and other agricultural chemicals

Polymer Additive

A reactive chemical used in the production of polycarbonates and other specialized polymers to enhance mechanical and thermal properties.

Benzyl chloroformate (50% in toluene) FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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