

Baclofen (CAS 1134-47-0) serves as a cornerstone in the United States API intermediates market, where its role as a high-purity fine chemical is essential for the domestic manufacture of muscle relaxants targeting spasticity associated with multiple sclerosis and spinal cord injuries. 4-Amino-3-(4-chlorophenyl)butanoic acid is increasingly sourced through specialized custom synthesis services by North American CDMOs who are prioritizing domestic supply chain resilience and cGMP compliance to mitigate risks from global sourcing shifts and meet rigorous FDA standards for Pharma/API purity 99%. beta-(Aminomethyl)-4-chlorobenzenepropanoic acid also finds critical utility as a general industry purity 98% building block for advanced neurological research and neuropharmacological diagnostic tools, driving sustained demand for a reliable bulk chemical supplier capable of providing exhaustive technical documentation and meeting American Chemical Society analytical benchmarks. We are an established Baclofen intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting Baclofen COA/TDS/SDS region-specific regulatory support, reliable lead times, worldwide supply chain capabilities


Baclofen (CAS 1134-47-0) serves as a cornerstone in the United States API intermediates market, where its role as a high-purity fine chemical is essential for the domestic manufacture of muscle relaxants targeting spasticity associated with multiple sclerosis and spinal cord injuries. 4-Amino-3-(4-chlorophenyl)butanoic acid is increasingly sourced through specialized custom synthesis services by North American CDMOs who are prioritizing domestic supply chain resilience and cGMP compliance to mitigate risks from global sourcing shifts and meet rigorous FDA standards for Pharma/API purity 99%. beta-(Aminomethyl)-4-chlorobenzenepropanoic acid also finds critical utility as a general industry pu...
Pharmaceutical
Pharmaceutical Actives & Precursors
Active Pharmaceutical Ingredients (APIs)
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Chemical Properties & Specifications
P201, P202, P261, P264, P270, P271, P272, P280, P284, P301+P310, P302+P352, P304+P340, P305+P351+P338, P308+P313, P312, P321, P330, P332+P313, P333+P313, P337+P313, P342+P311, P362+P364, P403+P233, P405, and P501
Acute Tox. 3 (100%)
Skin Irrit. 2 (96.4%)
A GABA-B receptor agonist used as an antispastic agent to relieve muscle spasms, cramping, and tightness caused by multiple sclerosis, spinal cord injuries, or other neurological diseases
A central nervous system depressant utilized in the formulation of oral tablets, solutions, and intrathecal injections for the management of reversible spasticity
A gamma-aminobutyric acid (GABA) derivative used in clinical studies to investigate treatments for alcohol use disorder and opioid withdrawal symptoms.
Baclofen is a gamma-aminobutyric acid (GABA) agonist and skeletal muscle relaxant used to treat muscle spasms, cramping, and tightness caused by conditions such as multiple sclerosis and spinal cord injuries
This compound is primarily used in the pharmaceutical industry for the production of antispastic medications and in medical research
Baclofen is compatible with oral tablets, oral solutions, suspensions, dissolvable granules, and intrathecal injections
Standard specifications include CAS number 1134-47-0, a molecular weight of 213.66, high purity (typically ≥99%), and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.