Azacyclonol

Azacyclonol

CAS Number
115-46-8
Molecular Formula
C₁₈H₂₁NO
Purity
99.87%

About Azacyclonol

Azacyclonol is a central nervous system (CNS) depressant with ataractic properties and historical relevance in antipsychotic research, particularly for its role in reducing hallucinations in psychotic conditions. It is also known as a major active metabolite of the antihistamine terfenadine and is identified by chemica...

Synonyms

  • Frenquel
  • Atractan
  • gamma-Pipradrol
  • Azacyclonol HCl
  • C18H21NO

Azacyclonol Specifications

CAS Number
115-46-8
Molecular Formula
C₁₈H₂₁NO
Molecular Weight
267.37 g/mol
IUPAC NameORBotanical Name
Diphenyl(piperidin-4-yl)methanol
Canonical SMILES
OC(c1ccccc1)(c2ccccc2)C3CCNCC3
InChI Key
ZMISODWVFHHWNR-UHFFFAOYSA-N
InChI
1S/C18H21NO/c20-18(15-7-3-1-4-8-15,16-9-5-2-6-10-16)17-11-13-19-14-12-17/h1-10,17,19-20H,11-14H2
EINECS Number
204-093-4
MDL Number
MFCD00003089
HSN No
2933.39.90
Molecular Weight
267.37 g/mol
Melting Point
160–163°C (320–325.4°F)
Purity
99.87%
Solubility
Moderately soluble in water; soluble in ethanol and DMSO
Form
Crystalline solid
Appearance
Beige powder or solid
Odor
Odorless
Boiling Point
821.65 K (calculated)
Hazard Statements
H302: Harmful if swallowed.nH315: Causes skin irritation.nH319: Causes serious eye irritation.

Metabolite Studies

A major active metabolite of the antihistamine terfenadine

Fexofenadine API Production

A core structural synthon utilised in downstream alkylation and oxidation steps to manufacture high-purity fexofenadine hydrochloride

Terfenadine Metabolite Profiling

An essential analytical standard used in metabolic tracking, pharmacokinetics, and toxicological validation loops within life science laboratories

Piperidine-Derived Synthons

A versatile heterocyclic building block employed in multi-step organic synthesis to insert stable diphenylmethane configurations

Antihistamine Drug Development

A secondary reactive precursor used in base-catalyzed drug discovery chemistry targeting histamine H1 receptors

Custom Chemical Masterbatches

A high-purity reaction component engineered for pharmaceutical pilot trials requiring exact organic trace metal control.

  1. Frenquel
  2. Atractan
  3. gamma-Pipradrol
  4. Azacyclonol HCl
  5. C18H21NO

Azacyclonol FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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