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ATS-8, chemically known as tert-butyl 2-[(4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate, is a crucial intermediate in the synthesis of Atorvastatin Calcium, a widely prescribed statin for lowering cholesterol levels. Its unique structure facilitates the construction of the heptanoic acid side chain essential for Atorvastatin's activity.
ATS-8, chemically known as tert-butyl 2-[(4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate, is a crucial intermediate in the synthesis of Atorvastatin Calcium, a widely prescribed statin for lowering cholesterol levels. Its unique structure facilitates the construction of the heptanoic acid side chain essential for Atorvastatin's activity.
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
Acute Toxicity (Oral, Dermal, Inhalation): Category 4 Skin Irritation: Category 2 Eye Irritation: Category 2A
H302: Harmful if swallowed. H312: Harmful in contact with skin. H332: Harmful if inhaled. H315: Causes skin irritation. H319: Causes serious eye irritation
P261: Avoid breathing dust/fume/gas/mist/vapors/spray. P264: Wash hands thoroughly after handling. P270: Do not eat, drink, or smoke when using this product. P271: Use only outdoors or in a well-ventilated area. P280: Wear protective gloves/protective clothing/eye protection/face protection. P301+P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. P302+P352: IF ON SKIN: Wash with plenty of water. P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P362+P364: Take off contaminated clothing and wash it before reuse. P501: Dispose of contents/container in accordance with local/regional/national/international regulations.
Used as a key intermediate in the synthesis of Atorvastatin Calcium, a widely prescribed statin medication for cholesterol reduction.
Functions as a crucial precursor in the development of (APIs) for lipid-lowering drugs.
Supports the production of cardiovascular drugs by enabling the construction of statin-related molecular frameworks.
Utilized in laboratory-scale and industrial R&D for developing next-generation cholesterol-lowering agents.
Store at room temperature (typically 15–30°C or 59–86°F).
Keep in a cool, dry, well-ventilated area, away from direct sunlight and incompatible materials such as strong oxidizing agents.
Store in original, tightly sealed containers to prevent contamination, degradation, and moisture absorption.
Available in 1 kg, 5 kg, 10 kg, and 25 kg containers. Custom packaging options can be provided upon request.
ATS-8 is a crucial intermediate used in the synthesis of Atorvastatin Calcium, a widely prescribed statin for lowering cholesterol levels.
It provides the heptanoic acid side chain required for the structural integrity and bioactivity of Atorvastatin Calcium.
Yes, ATS-8 is manufactured under strict pharmaceutical-grade conditions to meet regulatory requirements for API intermediates.
Wear protective gloves, clothing, and eye protection. Avoid inhalation of dust and ensure good ventilation during handling.
Yes, ATS-8 is suitable for large-scale production, and its stability makes it ideal for pharmaceutical manufacturing processes.
Yes, ATS-8 complies with REACH, FDA, ISO 9001, and other international safety and quality standards.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
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