ANECORTAVE ACETATE(H5/H6)

CAS Number: 7753-60-8

Molecular Formula: C23H30O5

About ANECORTAVE ACETATE(H5/H6)

Anecortave acetate (CAS 77535-39-8) stands as a pivotal angiostatic specialist for ophthalmic research, particularly specialized in inhibiting pathological neovascularization in exudative age-related macular degeneration and managing elevated intraocular pressure in glaucoma. As a premier bulk chemical supplier, we rec...

ANECORTAVE ACETATE(H5/H6) Specifications

CAS Number

7753-60-8

Molecular Formula

C23H30O5

Molecular Weight

386.49 g/mol

IUPAC Name

[2-[(8R,10S,13S,14R,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

Canonical SMILES

CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC=C3[C@H]2CCC4=CC(=O)CC[C@]43C)C)O

InChI Key

YUWPMEXLKGOSBF-GACAOOTBSA-N

PubChem CID

111332.0

CAS Number

7753-60-8

Molecular Formula

C23H30O5

Molecular Weight

386.49 g/mol

IUPAC Name

[2-[(8R,10S,13S,14R,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

Canonical SMILES

CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC=C3[C@H]2CCC4=CC(=O)CC[C@]43C)C)O

InChI Key

YUWPMEXLKGOSBF-GACAOOTBSA-N

PubChem CID

111332.0

Molecular Weight

386.49 g/mol

Physical appearance

White to off-white or light yellow powder to crystal

Angiogenesis Inhibitor

A novel angiostatic cortisene and potent anti-angiogenic agent utilized as a therapeutic candidate for the treatment of exudative (wet) age-related macular degeneration and the reduction of intraocular pressure in steroid-induced glaucoma

Pharmaceutical Research Tool

A functionalized analog of cortisol acetate employed in clinical studies to investigate the inhibition of neovascularization and the expression of plasminogen activator inhibitor-1 (PAI-1) in ocular neovascular diseases.