Amoxicillin Trihydrate (CAS 61336-70-7) is a foundational Semi-Synthetic, Broad-Spectrum Aminopenicillin API within the beta-lactam class, valued for its enhanced stability and superior oral bioavailability in its trihydrate form. Therapeutic power is rooted in its bactericidal mechanism, which involves irreversibly binding to & inactivating Penicillin-Binding Proteins (PBPs)-enzymes essential for the cross-linking of bacterial peptidoglycans - thereby inhibiting cell wall synthesis & leading to the fatal lysis of the microorganism. This mode of action makes Amoxicillin Trihydrate highly effective for treating a many array of susceptible infections across the respiratory, genitourinary, and skin systems, and it serves as a critical component in multi-drug regimens used for H. pylori eradication; furthermore, its functional properties often necessitate the use of specialized DC grades for tablet manufacturing, and its efficacy is commonly safeguarded by co-formulation with beta-lactamase inhibitors like Clavulanic Acid to combat bacterial resistance. We are the leading Amoxicillin Trihydrate supplier worldwide with multiple pharmacopeias ensuring comprehensive regulatory support & CoA traceability for various grades with global supply capability with reliable lead time.
Amoxicillin Trihydrate (CAS 61336-70-7) is a foundational Semi-Synthetic, Broad-Spectrum Aminopenicillin API within the beta-lactam class, valued for its enhanced stability and superior oral bioavailability in its trihydrate form. Therapeutic power is rooted in its bactericidal mechanism, which involves irreversibly binding to & inactivating Penicillin-Binding Proteins (PBPs)-enzymes essential for the cross-linking of bacterial peptidoglycans - thereby inhibiting cell wall synthesis & leading to the fatal lysis of the microorganism. This mode of action makes Amoxicillin Trihydrate highly effective for treating a many array of susceptible infections across the respiratory, genitourinary, and skin systems, and it serves as a critical component in multi-drug regimens used for H. pylori eradication; furthermore, its functional properties often necessitate the use of specialized DC grades for tablet manufacturing, and its efficacy is commonly safeguarded by co-formulation with beta-lactamase inhibitors like Clavulanic Acid to combat bacterial resistance. We are the leading Amoxicillin Trihydrate supplier worldwide with multiple pharmacopeias ensuring comprehensive regulatory support & CoA traceability for various grades with global supply capability with reliable lead time.
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Active Pharmaceutical Ingredients (APIs)
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Chemical Properties & Specifications
Treatment of infections of the ear, nose, throat (e.g., strep throat, tonsillitis), genitourinary tract, skin/skin structure, and lower respiratory tract (e.g., pneumonia, bronchitis) caused by susceptible beta-lactamase-negative microorganisms
Multi-drug regimens (often triple therapy with a proton pump inhibitor and a macrolide, like clarithromycin) to treat Helicobacter pylori infection and associated peptic ulcers
Prophylaxis against bacterial endocarditis in high-risk patients undergoing dental or surgical procedures
Frequently combined with a beta-lactamase inhibitor, such as clavulanic acid (e.g., Amoxicillin/Clavulanate), to extend its spectrum of activity against beta-lactamase-producing resistant bacteria.
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