Amlodipine Maleate

CAS Number: 88150-47-4

Molecular Formula: C24H29ClN2O9

Purity: Amlodipine Maleate 98% purity

About Amlodipine Maleate

Amlodipine Maleate (CAS 88150-47-4) remains a critical Active Pharmaceutical Ingredient in the North American cardiovascular market, where Pharma/API purity 99% is the benchmark for CDMOs developing next-generation antihypertensive fixed-dose combinations. (2Z)-2-Butenedioic acid compound with 3-ethyl 5-methyl 2-[(2-am...

Synonyms

Amlodipine
Amlodipine Besylate
Amlodipine Maleate
Amlodipine Maleate (1:1)
Amlodipine, (+-)-Isomer

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Amlodipine Maleate Specifications

CAS Number

88150-47-4

Molecular Formula

C24H29ClN2O9

Molecular Weight

524.95 g/mol

IUPAC Name

(Z)-but-2-enedioic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

Canonical SMILES

CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C(=CC(=O)O)C(=O)O

InChI Key

TZNOWAJJWCGILX-BTJKTKAUSA-N

InChI

InChI=1S/C20H25ClN2O5.C4H4O4/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;5-3(6)1-2-4(7)8/h5-8,17,23H,4,9-11,22H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

PubChem CID

6435922

HSN No

30049072

CAS Number

88150-47-4

Molecular Formula

C24H29ClN2O9

Molecular Weight

524.95 g/mol

IUPAC Name

(Z)-but-2-enedioic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

Canonical SMILES

CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C(=CC(=O)O)C(=O)O

InChI Key

TZNOWAJJWCGILX-BTJKTKAUSA-N

InChI

InChI=1S/C20H25ClN2O5.C4H4O4/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;5-3(6)1-2-4(7)8/h5-8,17,23H,4,9-11,22H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

PubChem CID

6435922

HSN No

30049072

Molecular Weight

524.95 g/mol

Purity

Amlodipine Maleate 98% purity

Antihypertensive Agent

A long-acting dihydropyridine calcium channel blocker used as a first-line treatment for hypertension to reduce blood pressure and lower the risk of fatal and nonfatal cardiovascular events, primarily stroke and myocardial infarction

Antianginal Agent

A potent coronary and peripheral vasodilator utilized for the symptomatic treatment of chronic stable angina and vasospastic angina (Prinzmetal's or variant angina) by improving oxygen delivery to the myocardial tissue

Pharmaceutical Intermediate

A high-purity crystalline salt used as a primary active pharmaceutical ingredient (API) in the formulation of oral solid dosage forms, including tablets and suspensions, often in combination with other cardiovascular medications like statins or ACE inhibitors

L-type Calcium Channel Blocker

A selective ion channel inhibitor employed in biochemical research to study the inhibition of voltage-dependent L-type calcium channels and its subsequent effects on vascular smooth muscle contractility and cellular apoptosis.