

Our Ambrettolide is a high-purity, 17-membered macrocyclic lactone that captures the elegant, diffusive essence of natural ambrette seed oil. Known for its exceptional "tenacity" (lasting up to a month on a blotter), (IFRA 51st Amendment Ambrettolide Status updated) acts as a powerful fixative that harmonizes floral and fruity notes while providing a sensual, "white flower" musky undertone. Unlike petroleum-based musks, our 2026 grade is 100% renewable carbon-based and readily biodegradable, making it the preferred choice for premium, environmentally conscious fine fragrances and personal care formulations for Buy Isoambrettolide CAS 28645-51-4 Bulk. We are an established Macrocyclic Musk Ambrettolide Supplier globally providing comprehensive analytical (HPLC/NMR/MS) and supporting quality assurance documentation (COA/TDS/SDS) across all grades, detailed impurity mapping; and region-specific regulatory support. We ensure reliable lead times from R&D quantities through commercial-scale manufacturing, enabling partners to meet diverse global and regional requirements.


Our Ambrettolide is a high-purity, 17-membered macrocyclic lactone that captures the elegant, diffusive essence of natural ambrette seed oil. Known for its exceptional "tenacity" (lasting up to a month on a blotter), (IFRA 51st Amendment Ambrettolide Status updated) acts as a powerful fixative that harmonizes floral and fruity notes while providing a sensual, "white flower" musky undertone. Unlike petroleum-based musks, our 2026 grade is 100% renewable carbon-based and readily biodegradable, making it the preferred choice for premium, environmentally conscious fine fragrances and personal care formulations for Buy Isoambrettolide CAS 28645-51-4 Bulk. We are an established Macrocyclic Musk Am...
Flavors & Fragrances
Fragrance Ingredients
Polycyclic Synthetic Musks
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Chemical Properties & Specifications
Enhances "radiance" and provides volume to iris, rose, and magnolia accords at trace concentrations (0.1–5%)
Imparts a luxurious, clean scent to shampoos, shower gels, and high-end lotions
Used in premium fabric softeners and detergents for long-lasting, sophisticated freshness
Approved (FEMA 4145) for use in trace amounts to add "mellowing" effects to fruit flavours like blackberry and pear
A staple in luxury scented candles and reed diffusers due to its high burning effectiveness and diffusion.
Under the IFRA 51st Amendment (2023–2026), Ambrettolide has no quantitative restrictions for any category, including Category 4 (Fine Fragrance). This makes it an incredibly safe and flexible tool for perfumers.
Ambrettolide shows "Good" stability in soaps, shampoos, and fabric conditioners (pH 6–10.5). However, its performance is rated as "Poor" in acid cleaners, liquid bleaches, and antiperspirants due to potential degradation in highly acidic or oxidizing environments.