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Adapalene (CAS 106685-40-9) serves as a cornerstone in the United States API intermediates market, where its role as a third-generation retinoid drives significant demand for high purity fine chemicals utilized in the synthesis of advanced dermatological formulations for acne and photoaging. Differin, the most recognized commercial iteration, has reshaped the domestic landscape through its transition to OTC status, prompting US-based CDMOs to prioritize custom synthesis services that meet a Pharma/API purity 99% standard to satisfy rigorous FDA and USP monographs. 6-(3-(adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid is also increasingly sought after by a reliable bulk chemical supplier for specialized applications in colorectal cancer research and anti-inflammatory drug development, requiring a General Industry purity 98% for preliminary laboratory assays and pilot-scale process optimization. We are an established Adapalene USP/BP api supplier with >= 99% purity for semi-finished formulators in the united states, providing comprehensive analytical (HPLC/NMR/MS) and supporting (Adapalene USP/BP) COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities
Adapalene (CAS 106685-40-9) serves as a cornerstone in the United States API intermediates market, where its role as a third-generation retinoid drives significant demand for high purity fine chemicals utilized in the synthesis of advanced dermatological formulations for acne and photoaging. Differin, the most recognized commercial iteration, has reshaped the domestic landscape through its transition to OTC status, prompting US-based CDMOs to prioritize custom synthesis services that meet a Pharma/API purity 99% standard to satisfy rigorous FDA and USP monographs. 6-(3-(adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid is also increasingly sought after by a reliable bulk chemical supplier fo...
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Active Pharmaceutical Ingredients (APIs)
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Chemical Properties & Specifications
P203, P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Skin Irrit. 2 (72.7%)
Eye Irrit. 2 (72.7%)
A topical retinoid used primarily in the formulation of gels, creams, and lotions for the treatment of acne vulgaris by modulating cellular keratinization and inflammatory processes
A selective agonist for RARβ and RARγ receptors employed in biochemical research to study gene transcription, cell differentiation, and the inhibition of hepatitis B virus transcription
A component used in the culturing of peripheral blood mononuclear cells (PBMC) and mixed lymphocyte reactions (MLR) to investigate effects on isolated macrophages
A certified reference material utilized in analytical laboratory testing and quality control assays for peak identification and potency verification according to USP/EP monographs.
Adapalene USP/BP is a third-generation topical retinoid and naphthoic acid derivative used primarily for the treatment of mild to moderate acne vulgaris by regulating skin cell turnover and providing anti-inflammatory effects
This compound is primarily used in the pharmaceutical and skincare industries for the production of prescription and over-the-counter acne treatments
Adapalene USP/BP is compatible with topical formulations such as aqueous gels, creams, lotions, and solutions, and is typically soluble in tetrahydrofuran or dimethyl sulfoxide for analytical purposes
Standard specifications include CAS number 106685-40-9, high purity (98.0% to 102.0% on a dried basis), and availability of documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
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