

8-Quinolinesulfonyl chloride (CAS 18704-37-5) is a critical reagent in the North American API intermediates market, primarily valued for its role in synthesizing sulfonamide-based pharmaceuticals and carbonic anhydrase inhibitors where a Pharma/API purity 99% is required to meet rigorous USP standards. Quinoline-8-sulfonyl chloride serves as one of the high purity fine chemicals increasingly sought by US-based CDMOs who are expanding custom synthesis services to strengthen domestic drug substance supply chains and reduce reliance on volatile global sourcing. Sulfonyl chloride, 8-quinoline- is also gaining traction in material science and agrochemical applications at a General Industry purity 98%, where its ability to facilitate regioselective functionalization at the 8-position makes it a staple for a reliable bulk chemical supplier supporting advanced research in the United States. We are an established 8-Quinolinesulfonyl chloride intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting 8-Quinolinesulfonyl chloride COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities

8-Quinolinesulfonyl chloride (CAS 18704-37-5) is a critical reagent in the North American API intermediates market, primarily valued for its role in synthesizing sulfonamide-based pharmaceuticals and carbonic anhydrase inhibitors where a Pharma/API purity 99% is required to meet rigorous USP standards. Quinoline-8-sulfonyl chloride serves as one of the high purity fine chemicals increasingly sought by US-based CDMOs who are expanding custom synthesis services to strengthen domestic drug substance supply chains and reduce reliance on volatile global sourcing. Sulfonyl chloride, 8-quinoline- is also gaining traction in material science and agrochemical applications at a General Industry purity...
Industrial Chemicals
Organic Intermediates
Chlorinated Aromatic Compounds
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Chemical Properties & Specifications
P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, and P501
Skin Corr. 1C (100%)
An important building block utilized in the synthesis of various biologically active quinoline-derived compounds, including anti-inflammatory, antibacterial, antiviral, and antimalarial agents
A versatile sulfonylating agent used to introduce sulfonamide or sulfonate groups into organic molecules, frequently employed in the development of molecular libraries and peptide bond formation
A critical precursor in the production of compounds with pesticidal, fungicidal, or herbicidal properties leveraging the bioactive nature of the quinoline core
A specialized reagent used in the synthesis of fluorescent probes and ligands for metal ions, facilitating the detection and quantification of biomolecules in research and laboratory settings.
8-Quinolinesulfonyl chloride is a versatile chemical compound and reactive building block used in organic synthesis and pharmaceutical research for the development of bioactive molecules, pharmaceuticals targeting infectious diseases and cancer, and fluorescent probes
This compound is widely used in the pharmaceutical, agrochemical, and material science industries for drug discovery, crop protection, and the development of photoactive materials
It is soluble in methanol and is used as a sulfonylating agent to form sulfonamides, sulfonates, and thioethers in liquid-phase organic synthesis
Specifications include CAS number 18704-37-5, purity of ≥98%, a melting point of 126-132°C, and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
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