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8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione (CAS NO : 666816-98-4)

8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine (CAS 666816-98-4) is a critical building block in the high purity fine chemicals segment, specifically serving as a key precursor for the synthesis of Linagliptin within the competitive US API intermediates market. 8-Bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione is increasingly sourced by domestic CDMOs who require Pharma/API purity 99% to ensure compliance with stringent FDA quality systems while navigating global sourcing shifts toward more resilient North American supply chains. 3-Methyl-7-(2-butyn-1-yl)-8-bromoxanthine remains indispensable for custom synthesis services and advanced pharmaceutical research where a General Industry purity 98% is often utilized for initial process optimization, highlighting the need for a reliable bulk chemical supplier capable of providing rigorous analytical validation. We are an established 8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting 8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities

8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione
8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione

8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine (CAS 666816-98-4) is a critical building block in the high purity fine chemicals segment, specifically serving as a key precursor for the synthesis of Linagliptin within the competitive US API intermediates market. 8-Bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione is increasingly sourced by domestic CDMOs who require Pharma/API purity 99% to ensure compliance with stringent FDA quality systems while navigating global sourcing shifts toward more resilient North American supply chains. 3-Methyl-7-(2-butyn-1-yl)-8-bromoxanthine remains indispensable for custom synthesis services and advanced pharmaceutical research where a General Industry ...

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Pharmaceutical Actives & Precursors

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Intermediates & Precursors

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Chemical Properties & Specifications

Applications of 8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione

Pharmaceutical Intermediate

A critical organic building block and precursor primarily used in the multi-step synthesis of the dipeptidyl peptidase-4 (DPP-4) inhibitor linagliptin for the management of type 2 diabetes

Organic Synthesis Building Block

A functionalized xanthine derivative employed in medicinal chemistry research and industrial manufacturing to develop complex heterocyclic molecules with diverse biological activities

Chemical Reference Material

A high-purity standard used in analytical laboratories for quality control, impurity profiling, and structural elucidation during the production of bulk drug substances.

Have Questions About 8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione?
We've Got Answers.

8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione is a heterocyclic building block and pharmaceutical intermediate primarily used in the synthesis of Linagliptin, a medication for type 2 diabetes

This compound is widely used in the pharmaceutical industry for drug discovery, research, and the production of active pharmaceutical ingredients

It is slightly soluble in DMSO and methanol and is typically handled as a solid powder or crystal for organic synthesis and laboratory research

Standard specifications include CAS number 666816-98-4, high purity (typically >=98% or >=99%), and documentation such as COA, TDS, impurity reports, and regulatory compliance documents

Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time

The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.

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