6,7-Dimethoxy-3,4-dihydroisoquinoline

CAS Number: 3382-18-1

Molecular Formula: C11H13NO2

Alkaloid Chemistry: Papaverine I emetine derivativesMedicinal Chemistry: Bioactive isoquinoline Building blockDehydrogenation Study: Mercury(II) acetate-mediated transformation M-HSynthetic Methodology: Reissert compound chemistry I heterocyclic synthesis

About 6,7-Dimethoxy-3,4-dihydroisoquinoline

Commercial demand is concentrated across states leading domestic pharmaceutical manufacturing, biotechnology innovation, and advanced organic synthesis. High-capacity API synthesis facilities in New Jersey, North Carolina, Pennsylvania, Indiana, California, and Texas rely on 6,7-Dimethoxy-3,4-dihydroisoquinoline to man...

Synonyms

C11H13NO2
AC1L1IQ8
Boc-2-fluoro-D-phenylalanine
KSC571E8H
NSLJVQUDZCZJLK-UHFFFAOYSA-N

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6,7-Dimethoxy-3,4-dihydroisoquinoline Specifications

CAS Number

3382-18-1

Molecular Formula

C11H13NO2

Molecular Weight

191.23 g/mol

IUPAC Name

6,7-dimethoxy-3,4-dihydroisoquinoline

Canonical SMILES

COC1=C(C=C2C=NCCC2=C1)OC

InChI Key

NSLJVQUDZCZJLK-UHFFFAOYSA-N

InChI

InChI=1S/C11H13NO2/c1-13-10-5-8-3-4-12-7-9(8)6-11(10)14-2/h5-7H,3-4H2,1-2H3

PubChem CID

30058

UNII Code

D6LM439T76

DSSTox Substance ID

DTXSID90187475

EINECS Number

222-185-9

MDL Number

MFCD00266748

CAS Number

3382-18-1

Molecular Formula

C11H13NO2

Molecular Weight

191.23 g/mol

IUPAC Name

6,7-dimethoxy-3,4-dihydroisoquinoline

Canonical SMILES

COC1=C(C=C2C=NCCC2=C1)OC

InChI Key

NSLJVQUDZCZJLK-UHFFFAOYSA-N

InChI

InChI=1S/C11H13NO2/c1-13-10-5-8-3-4-12-7-9(8)6-11(10)14-2/h5-7H,3-4H2,1-2H3

PubChem CID

30058

UNII Code

D6LM439T76

DSSTox Substance ID

DTXSID90187475

EINECS Number

222-185-9

MDL Number

MFCD00266748

Molecular Weight

191.23 g/mol

XLogP3

1.3

Hydrogen Bond Acceptor Count

Rotatable Bond Count

Monoisotopic Mass

191.094628657 Da

GHS Hazard Statements

H315 (100%): Causes skin irritation H319 (100%): Causes serious eye irritation

Hazard Classes and Categories

Skin Irrit. 2 (100%) Eye Irrit. 2 (100%)

Cardiovascular Pharmaceutical Synthesis

A foundational structural building block in the commercial synthesis of alpha-adrenergic receptor antagonists, antihypertensive agents, and specialised coronary vasodilators

Tetrahydroisoquinoline (THIQ) Derivative Engineering

A high-purity starting material for asymmetric reduction and catalytic hydrogenation cascades targeting complex THIQ matrices and therapeutic chiral synthons

Targeted Alkaloid & Natural Product Analogues

A precise heterocyclic scaffold utilised in medicinal chemistry discovery programs to construct complex isoquinoline alkaloid frameworks, emetine analogues, and bioactive open-ring structures

Custom CDMO Small Molecule Scale-Up

A critical pipeline intermediate optimised for high-yield condensation and Pictet-Spengler-type cyclisations within commercial contract development and manufacturing architectures

Advanced Organic Synthesis & Heterocyclic R&D

A highly reactive, dimethoxy-substituted bicyclic core engineered for selective electrophilic substitution, alkylation, and transition-metal-catalysed coupling methodologies