

5-Methyl-4-isoxazolecarboxylic acid (CAS 42831-50-5) is a vital building block in the API intermediates market, primarily serving as the primary precursor for the synthesis of Leflunomide and other isoxazole-based therapeutics where a Pharma/API purity 99% is mandatory to meet stringent FDA quality standards. 5-Methylisoxazole-4-carboxylic acid is increasingly sought after by US-based CDMOs who provide custom synthesis services to pharmaceutical innovators looking to shorten lead times and navigate global sourcing shifts by securing high purity fine chemicals within domestic supply chains. 4-Isoxazolecarboxylic acid, 5-methyl- is also utilized in general industry applications at a purity of 98%, where its functionalized heterocyclic core acts as a high-performance intermediate for specialty agrochemical development, driving the need for a reliable bulk chemical supplier capable of providing robust technical documentation and regulatory compliance. We are an established 5-Methyl-4-isoxazolecarboxylic acid intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting 5-Methyl-4-isoxazolecarboxylic acid COA/TDS/SDS region-specific regulatory support, reliable lead times, worldwide supply chain capabilities


5-Methyl-4-isoxazolecarboxylic acid (CAS 42831-50-5) is a vital building block in the API intermediates market, primarily serving as the primary precursor for the synthesis of Leflunomide and other isoxazole-based therapeutics where a Pharma/API purity 99% is mandatory to meet stringent FDA quality standards. 5-Methylisoxazole-4-carboxylic acid is increasingly sought after by US-based CDMOs who provide custom synthesis services to pharmaceutical innovators looking to shorten lead times and navigate global sourcing shifts by securing high purity fine chemicals within domestic supply chains. 4-Isoxazolecarboxylic acid, 5-methyl- is also utilized in general industry applications at a purity of ...
Industrial Chemicals
Organic Intermediates
Aromatic Carboxylic Acids & Derivatives
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Chemical Properties & Specifications
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Skin Irrit. 2 (53.8%)
Eye Dam. 1 (30.8%)
A key building block utilized in the commercial synthesis of autoimmune disorder medications, specifically acting as the primary precursor for the production of Leflunomide and Teriflunomide
A functionalized heterocyclic compound employed in the formulation of herbicides and fungicides to enhance efficacy and improve crop yields
A versatile isoxazole derivative used in academic and industrial research for the development of bioactive molecules and novel peptidomimetics
A high-purity reference material used in analytical chemistry for the quantification of related substances and identification of impurities in pharmaceutical manufacturing.
5-Methyl-4-isoxazolecarboxylic acid, also known as 5-methylisoxazole-4-carboxylic acid, is a heterocyclic organic compound that serves as a key pharmaceutical intermediate, particularly in the synthesis of Leflunomide and Teriflunomide for treating autoimmune diseases like rheumatoid arthritis
This compound is primarily used in the pharmaceutical and agrochemical industries for drug discovery, the production of anti-inflammatory medications, and the formulation of herbicides
It is soluble in organic solvents like methanol and ethanol, and is typically used as a building block in liquid-phase chemical synthesis and derivatization reactions such as esterification and amidation
Standard specifications include CAS number 42831-50-5, molecular weight 127.10, high purity (typically ≥98.5% or ≥99%), and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
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