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5-bromo-2-chloro-N- cyclopentylpyrimidin-4- amine

5-bromo-2-chloro-N- cyclopentylpyrimidin-4- amine

CAS Number: 733039-20-8

Molecular Formula: C9H11BrClN3

Purity: 5-bromo-2-chloro-N-cyclopentylpyrimidin-4-amine 97% purity

About 5-bromo-2-chloro-N- cyclopentylpyrimidin-4- amine

5-bromo-2-chloro-N-cyclopentylpyrimidin-4-amine (CAS 733039-20-8) functions as a critical scaffold for the synthesis of CDK4/6 inhibitors, where the rising demand for Pharma/API purity 99% is driving US-based CDMOs to integrate advanced custom synthesis services to ensure strict isomeric control and yield optimization ...

5-bromo-2-chloro-N- cyclopentylpyrimidin-4- amine Specifications

CAS Number

733039-20-8

Molecular Formula

C9H11BrClN3

Molecular Weight

276.56 g/mol

IUPAC Name

5-bromo-2-chloro-N-cyclopentylpyrimidin-4-amine

Canonical SMILES

C1CCC(C1)NC2=NC(=NC=C2Br)Cl

InChI Key

DIVUXBABVYOIOT-UHFFFAOYSA-N

CAS Number

733039-20-8

Molecular Formula

C9H11BrClN3

Molecular Weight

276.56 g/mol

IUPAC Name

5-bromo-2-chloro-N-cyclopentylpyrimidin-4-amine

Canonical SMILES

C1CCC(C1)NC2=NC(=NC=C2Br)Cl

InChI Key

DIVUXBABVYOIOT-UHFFFAOYSA-N

Molecular Weight

276.56 g/mol

Purity

5-bromo-2-chloro-N-cyclopentylpyrimidin-4-amine 97% purity

pKa

1.22±0.10

Pharmaceutical Intermediate

A premier building block and key precursor used in the synthesis of advanced medicinal compounds, particularly for the production of cyclin-dependent kinase (CDK) inhibitors like Ribociclib and Palbociclib for cancer treatment

Heterocyclic Building Block

A functionalized pyrimidine derivative utilized in organic synthesis and medicinal chemistry research for sequential functionalization and the development of complex molecules with diverse biological activities.

5-bromo-2-chloro-N- cyclopentylpyrimidin-4- amine FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

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