4-Nitrophenyl chloroformate

CAS Number: 7693-46-1

Molecular Formula: C7H4ClNO4

Purity: 4-Nitrophenyl chloroformate 96% purity

About 4-Nitrophenyl chloroformate

4-Nitrophenyl chloroformate (CAS 7693-46-1) remains a cornerstone reagent for the synthesis of high purity fine chemicals, particularly in the formation of active carbonates and carbamates where Pharma/API purity 99% is essential for US-based CDMOs looking to minimize side-chain impurities in complex peptide coupling. ...

Synonyms

4-Nitrophenyl chloroformate
7693-46-1
4-Nitrophenyl carbonochloridate
Chloroformic acid 4-nitrophenyl ester
Carbonochloridic acid, 4-nitrophenyl ester

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4-Nitrophenyl chloroformate Specifications

CAS Number

7693-46-1

Molecular Formula

C7H4ClNO4

Molecular Weight

201.56 g/mol

IUPAC Name

(4-nitrophenyl) carbonochloridate

Canonical SMILES

C1=CC(=CC=C1[N+](=O)[O-])OC(=O)Cl

InChI Key

NXLNNXIXOYSCMB-UHFFFAOYSA-N

InChI

InChI=1S/C7H4ClNO4/c8-7(10)13-6-3-1-5(2-4-6)9(11)12/h1-4H

PubChem CID

82129

HSN No

29151290

CAS Number

7693-46-1

Molecular Formula

C7H4ClNO4

Molecular Weight

201.56 g/mol

IUPAC Name

(4-nitrophenyl) carbonochloridate

Canonical SMILES

C1=CC(=CC=C1[N+](=O)[O-])OC(=O)Cl

InChI Key

NXLNNXIXOYSCMB-UHFFFAOYSA-N

InChI

InChI=1S/C7H4ClNO4/c8-7(10)13-6-3-1-5(2-4-6)9(11)12/h1-4H

PubChem CID

82129

HSN No

29151290

Molecular Weight

201.56 g/mol

Purity

4-Nitrophenyl chloroformate 96% purity

Peptide Synthesis Reagent

A versatile coupling agent and building block used in solid-phase peptide synthesis (SPPS) to link amino acids, facilitate the formation of peptide chains, and obtain altered side chain functionalities

Organic Synthesis Intermediate

A highly reactive reagent employed for the activation of amines, alcohols, and thiols to produce ureas, carbamates, and carbonates, as well as for the protection of amine groups and the synthesis of isocyanates

Pharmaceutical and Biomedical Research Reagent

A critical coupling agent used to join drug molecules with carrier molecules like polyrotaxane and to enable the covalent attachment of peptides to macromers for the development of functionalized polymer networks and prodrugs

Resin and Surface Activation Agent

A functional reagent used for the immobilization of enzymes and other biomolecules onto surfaces and for the activation of resins in combinatorial chemistry.