

4-Methylthiobenzyl cyanide (CAS 18991-39-4) is a high-performance organosulfur intermediate essential to the American fine chemicals market, where its unique alliaceous profile and controlled reactivity enable the precision synthesis of advanced thiazole derivatives and bioactive pharmaceutical scaffolds. Within the U.S. fragrance and flavor sector, this potent aroma chemical is a critical building block for creating depth and savory nuances in complex olfactory formulations, frequently outperforming traditional sulfur-based reagents in both stability and yield. Furthermore, the compound is seeing robust demand across domestic agrochemical and CDMO sectors as a versatile reagent for introducing thioether groups into complex molecular structures, driving innovation in process chemistry and commercial-scale manufacturing. As an established supplier of high-purity 4-methylthiobenzyl cyanide, we provide dependable supply, consistent quality, and comprehensive regulatory documentation, including CoA and TDS for all grades. Beyond chemical supply, we support our partners through the entire product lifecycle—from route scouting and formulation development to scale-up, process optimization, and pilot-to-commercial manufacturing. Our teams also provide expert assistance with GMP-compliant quality assurance, regulatory filings, and global supply chain logistics.


4-Methylthiobenzyl cyanide (CAS 18991-39-4) is a high-performance organosulfur intermediate essential to the American fine chemicals market, where its unique alliaceous profile and controlled reactivity enable the precision synthesis of advanced thiazole derivatives and bioactive pharmaceutical scaffolds. Within the U.S. fragrance and flavor sector, this potent aroma chemical is a critical building block for creating depth and savory nuances in complex olfactory formulations, frequently outperforming traditional sulfur-based reagents in both stability and yield. Furthermore, the compound is seeing robust demand across domestic agrochemical and CDMO sectors as a versatile reagent for introduc...
Elemental Derivatives
Miscellaneous Functional Intermediates
General Functional Reagents
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Chemical Properties & Specifications
an intermediate for the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals
an aroma chemical used in fine perfumes, cosmetics, and industrial fragrance applications to provide alliaceous, savory, or spicy scent profiles
a reagent used for the synthesis of active pharmaceutical ingredients (APIs), COX-2 inhibitors, and tert-butyl peresters
4-Methyl Thio Benzyl Cyanide, also known as 4-(methylthio)phenylacetonitrile, is a versatile chemical intermediate and aroma compound used in the synthesis of pharmaceuticals, agrochemicals, and specialty fragrance chemicals
This compound is primarily used in the fragrance, pharmaceutical, agrochemical, and specialty chemical industries
It is insoluble in water but soluble in organic solvents such as ethanol, oils, and esters, making it compatible with liquid-phase synthesis and various fragrance or cosmetic formulations
Standard specifications include CAS numbers 18991-39-4 or 38746-92-8, high purity (typically 98-99%), and available documentation such as COA, TDS, SDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, though smaller quantities like 25 kgs may be available, with international lead times depending on the shipping destination.
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