

4-Methylbenzene-1,2-diol (CAS 452-86-8) is a vital building block in the high purity fine chemicals sector, where Pharma/API purity 99% is increasingly demanded by North American CDMOs for the synthesis of advanced neuroprotective and anti-inflammatory API intermediates. Homocatechol is witnessing a significant surge in the API intermediates market as US-based manufacturers pivot toward domestic custom synthesis services to secure resilient supply chains and ensure strict adherence to American Chemical Society quality benchmarks. 3,4-Dihydroxytoluene remains a versatile component for general industry purity 98% applications, particularly as a specialized antioxidant and stabilizer in flavor and fragrance formulations, driving the need for a reliable bulk chemical supplier capable of navigating evolving US regulatory landscapes. We are an established 4-Methyl Catechol intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting 4-Methyl Catechol COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities


4-Methylbenzene-1,2-diol (CAS 452-86-8) is a vital building block in the high purity fine chemicals sector, where Pharma/API purity 99% is increasingly demanded by North American CDMOs for the synthesis of advanced neuroprotective and anti-inflammatory API intermediates. Homocatechol is witnessing a significant surge in the API intermediates market as US-based manufacturers pivot toward domestic custom synthesis services to secure resilient supply chains and ensure strict adherence to American Chemical Society quality benchmarks. 3,4-Dihydroxytoluene remains a versatile component for general industry purity 98% applications, particularly as a specialized antioxidant and stabilizer in flavor ...
Pharmaceutical
Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
P261, P264+P265, P272, P280, P302+P352, P305+P351+P338, P321, P333+P317, P337+P317, P362+P364, and P501
Skin Sens. 1 (96.4%)
Eye Irrit. 2A (100%)
A critical building block used in the synthesis of various drug molecules, particularly those involving catechol or phenol functionalities
A versatile organic compound commonly employed in the synthesis of agrochemicals, fine chemicals, and specialty polymers
An essential starting material used in the manufacturing of aroma compounds, most notably for the production of the watermelon ketone fragrance
A phenolic agent utilized in industrial formulations and rubber production to prevent oxidative degradation and scavenge free radicals
A potent bioactive molecule used in scientific research to stimulate the synthesis of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF).
4-Methyl Catechol, also known as 4-methylbenzene-1,2-diol or homocatechol, is an organic compound that acts as a potent antioxidant, a human metabolite, and an inducer of nerve growth factor
This compound is primarily used in the pharmaceutical, agrochemical, and materials science industries for the synthesis of drugs, antimicrobials, and redox-active ligands
It is soluble in water, DMSO, ethanol, DMF, and methanol, and it is typically handled as a solid powder or crystalline flakes
Standard specifications include CAS number 452-86-8, high purity (typically >=95% or >=98%), molecular weight 124.14, and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
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