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4-Fluoro-2-methoxy-5-nitrobenzenamine

4-Fluoro-2-methoxy-5-nitrobenzenamine

CAS Number: 1075705-01-9

Molecular Formula: C7H7FN2O3

About 4-Fluoro-2-methoxy-5-nitrobenzenamine

4-Fluoro-2-methoxy-5-nitrobenzenamine (CAS 1075705-01-9) is increasingly utilized as a critical high purity fine chemical intermediate in the pharmaceutical industry, specifically for the synthesis of Osimertinib and other tyrosine kinase inhibitors used in targeted cancer therapies. 4-Fluoro-5-nitro-o-anisidine is cur...

4-Fluoro-2-methoxy-5-nitrobenzenamine Specifications

CAS Number

1075705-01-9

Molecular Formula

C7H7FN2O3

Molecular Weight

186.14 g/mol

IUPAC Name

4-fluoro-2-methoxy-5-nitroaniline

Canonical SMILES

COC1=CC(=C(C=C1N)[N+](=O)[O-])F

InChI Key

FYSIGSQCZXQTIH-UHFFFAOYSA-N

PubChem CID

57429072

CAS Number

1075705-01-9

Molecular Formula

C7H7FN2O3

Molecular Weight

186.14 g/mol

IUPAC Name

4-fluoro-2-methoxy-5-nitroaniline

Canonical SMILES

COC1=CC(=C(C=C1N)[N+](=O)[O-])F

InChI Key

FYSIGSQCZXQTIH-UHFFFAOYSA-N

PubChem CID

57429072

Molecular Weight

186.14 g/mol

Physical appearance

Light yellow to Brown powder to crystal

Pharmaceutical Intermediate

A critical organic building block primarily used as a key starting material and intermediate in the synthesis of the EGFR tyrosine kinase inhibitor Osimertinib (Tagrisso) and the mutant BRAFV600E kinase inhibitor Mereletinib for cancer treatment

Organic Synthesis Building Block

A versatile functionalized aniline derivative employed in academic and industrial research for the development of complex pharmaceutical and bioactive molecules

Dye Intermediate

A specialized starting material utilized in the synthesis of disazo disperse dyes for industrial applications such as the dyeing of polyester fibers.

4-Fluoro-2-methoxy-5-nitrobenzenamine FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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