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4-(4-Methylphenoxy)benzylamine hydrochloride (CAS No. 262862-66-8) is a versatile aromatic amine intermediate commonly used in the United States within the agrochemical and pharmaceutical industries. It serves as a building block for synthesizing complex bioactive molecules and crop protection agents. In agrochemical synthesis, it plays a key role in the manufacture of insecticides such as tolfenpyrad and other performance chemicals, where high purity and controlled reactivity are critical to yield and efficacy. It is a white to light-yellow powder form, supplied with high assay (≥ 99.0%), allowing it to participate in diverse chemical transformations and support the development of novel crop protection solutions and performance chemicals. In Elemental Derivatives and Pharmaceutical hierarchy, it serves as the indispensable structural building block for the synthesis of Vortioxetine (an atypical antidepressant). As an established 4-(4-Methylphenoxy)benzylamine hydrochloride manufacturer and supplier in the USA, we offer 4-4-methylphenoxy-benzylamine-hydrochloride intermediate with high purity (≥ 99.0% (Validated by HPLC) and technical documentation, including Certificates of Analysis (CoA) and Safety Data Sheets (SDS), to support research and production needs across pharmaceutical R&D, crop protection development, and industrial chemical synthesis. We offer this product with reliable lead times and commercially competitive USD-based pricing.
4-(4-Methylphenoxy)benzylamine hydrochloride (CAS No. 262862-66-8) is a versatile aromatic amine intermediate commonly used in the United States within the agrochemical and pharmaceutical industries. It serves as a building block for synthesizing complex bioactive molecules and crop protection agents. In agrochemical synthesis, it plays a key role in the manufacture of insecticides such as tolfenpyrad and other performance chemicals, where high purity and controlled reactivity are critical to yield and efficacy. It is a white to light-yellow powder form, supplied with high assay (≥ 99.0%), allowing it to participate in diverse chemical transformations and support the development of novel cro...
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Agrochemicals
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Agrochemical Intermediates
Aromatic Amines & Chlorinated Intermediates
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Chemical Properties & Specifications
Phenoxyphenyl-methylamine scaffold - privileged structure in the development of novel Fungicides and Herbicides that target specific enzyme sites in plant pathogens, utilizing the ether-linked aromatic rings for optimized lipophilicity
Significant in Synthesis of Vortioxetine Hydrobromide. TOBA HCl-coupled with 2-(2,4-dimethylphenylthio)benzene derivatives to form the core of the antidepressant molecule
Functionalizing agent in the creation of specialized polymers and resins where an aromatic ether-linked amine moiety is required to enhance thermal or chemical resistance
Stable under recommended storage conditions
Sensitive to prolonged exposure to air and moisture which may lead to carbonate formation of the amine
Store in a cool, dry, well-ventilated area. Keep containers tightly closed
Recommended storage temperature: 15°C to 25°C
HCl salt form (CAS 262862-66-8) is significantly more stable, crystalline, and easier to handle in a production environment compared to the free base, which can be prone to oxidation and carbon dioxide absorption. This ensures higher titer and longer shelf life.
Our TOBA HCI is dried to a moisture content of ≤ 0.5%. Low moisture is critical for subsequent N-arylation or amidation steps where water can quench reactive catalysts or intermediates, leading to reduced yields.
Our process minimizes the presence of 4-methylphenol (p-cresol) and residual benzyl chloride derivatives. We maintain total impurities at < 1.0%, with individual unknown impurities below 0.10%, supporting seamless integration into validated API processes.
With our optimized synthesis route and robust inventory management, we offer reliable lead times ranging from 4 to 8 weeks for bulk global shipments, ensuring your API production timelines remain uninterrupted.
Yes export ready with TOBA hcl coa, TOBA
