4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one (NPP-14) (CAS NO : 79560-19-3)

4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one, commonly known as Tetralone, is an intermediate in the synthesis of Sertraline, a selective serotonin reuptake inhibitor (SSRI) used to treat depression and anxiety disorders. Tetralone serves as a key building block in the pharmaceutical manufacturing process of Sertraline.

Industries

Pharmaceutical

Sub-category

Intermediates & Precursors

Fast Response

Get a Quote

Details add in quote!

Minimum Order Quantity

Included in Quote

Lead Time

Included in Quote

Regional Availability

Included in Quote

Incoterms

Included in Quote

Chemical Properties & Specifications

Applications of 4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one (NPP-14)

Pharmaceutical Industry

Used as an intermediate in the synthesis of Sertraline.

Research & Development

Serves in the development of other bioactive molecules and as a reference standard in analytical studies.

Have Questions About 4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one (NPP-14)?
We've Got Answers.

What is the primary application of 4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one in the pharmaceutical industry?

Tetralone is primarily used as an intermediate in the synthesis of Sertraline, a selective serotonin reuptake inhibitor (SSRI) used to treat depression and anxiety disorders.

How does 4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one contribute to the synthesis of Sertraline?

Tetralone serves as a precursor in the synthesis of Sertraline, providing key functional groups that are essential for the final bioactive structure of the medication.

Is 4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one safe to handle in a laboratory setting?

Yes, Tetralone should be handled with care. Personal protective equipment (PPE), including gloves, goggles, and lab coats, is recommended to prevent direct contact. Follow standard laboratory safety procedures when handling this intermediate.

What analytical methods are typically used to detect 4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one?

Tetralone is commonly analyzed using High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to monitor the synthesis process and ensure the purity of Sertraline.