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3-methyl-n-(trifluoroacetyl)-L-valine

3-methyl-n-(trifluoroacetyl)-L-valine

CAS Number: 666832-71-9

Molecular Formula: C8H12F3NO3

About 3-methyl-n-(trifluoroacetyl)-L-valine

3-Methyl-N-(trifluoroacetyl)-L-valine (CAS 666832-71-9) serves as a critical pharmaceutical intermediate with 99% purity, specialized in the convergent synthesis of the antiviral protease inhibitor nirmatrelvir, where its role as a high purity fine chemicals building block is essential for meeting the stringent United ...

3-methyl-n-(trifluoroacetyl)-L-valine Specifications

CAS Number

666832-71-9

Molecular Formula

C8H12F3NO3

Molecular Weight

227.18 g/mol

IUPAC Name

(2S)-3,3-dimethyl-2-[(2,2,2-trifluoroacetyl)amino]butanoic acid

Canonical SMILES

CC(C)(C)[C@@H](C(=O)O)NC(=O)C(F)(F)F

InChI Key

FCTPLAZWXGEGKO-SCSAIBSYSA-N

PubChem CID

61143129

CAS Number

666832-71-9

Molecular Formula

C8H12F3NO3

Molecular Weight

227.18 g/mol

IUPAC Name

(2S)-3,3-dimethyl-2-[(2,2,2-trifluoroacetyl)amino]butanoic acid

Canonical SMILES

CC(C)(C)[C@@H](C(=O)O)NC(=O)C(F)(F)F

InChI Key

FCTPLAZWXGEGKO-SCSAIBSYSA-N

PubChem CID

61143129

Molecular Weight

227.18 g/mol

Physical appearance

White to off-white Solid

Pharmaceutical Intermediate

A key pharmaceutical intermediate utilized primarily as a precursor in the chemical synthesis of the oral SARS-CoV-2 main protease (Mpro) inhibitor nirmatrelvir, the active antiviral component of Paxlovid used for the treatment of COVID-19

Organic Synthesis Building Block

A functionalized amino acid derivative employed in the preparation of nitrile-containing antiviral compounds and other complex medicinal substances requiring N-trifluoroacetyl protection.

3-methyl-n-(trifluoroacetyl)-L-valine FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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