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(2S,3R)-3-(3,4-bis(benzyloxy)phenyl)-2-amino-3-hydroxypropanoic acid

(2S,3R)-3-(3,4-bis(benzyloxy)phenyl)-2-amino-3-hydroxypropanoic acid

CAS Number: 106887-48-3

Molecular Formula: C23H23NO5

About (2S,3R)-3-(3,4-bis(benzyloxy)phenyl)-2-amino-3-hydroxypropanoic acid

(2S,3R)-3-(3,4-bis(benzyloxy)phenyl)-2-amino-3-hydroxypropanoic acid (CAS 106887-48-3) is a critical threo-configured precursor in the synthesis of Droxidopa, where its Pharma/API purity 99% is essential for US-based CDMOs managing complex chiral molecules. (2S,3R)-2-Amino-3-(3,4-bis(benzyloxy)phenyl)-3-hydroxypropanoi...

(2S,3R)-3-(3,4-bis(benzyloxy)phenyl)-2-amino-3-hydroxypropanoic acid Specifications

CAS Number

106887-48-3

Molecular Formula

C23H23NO5

Molecular Weight

393.44 g/mol

IUPAC Name

(2S,3R)-2-amino-3-[3,4-bis(phenylmethoxy)phenyl]-3-hydroxypropanoic acid

Canonical SMILES

C1=CC=C(C=C1)COC2=C(C=C(C=C2)[C@H]([C@@H]\(C\(=O\)O\)N)O)OCC3=CC=CC=C3

InChI Key

QNOUABMNRMROSL-UHFFFAOYSA-N

CAS Number

106887-48-3

Molecular Formula

C23H23NO5

Molecular Weight

393.44 g/mol

IUPAC Name

(2S,3R)-2-amino-3-[3,4-bis(phenylmethoxy)phenyl]-3-hydroxypropanoic acid

Canonical SMILES

C1=CC=C(C=C1)COC2=C(C=C(C=C2)[C@H]([C@@H]\(C\(=O\)O\)N)O)OCC3=CC=CC=C3

InChI Key

QNOUABMNRMROSL-UHFFFAOYSA-N

Molecular Weight

393.44 g/mol

Pharmaceutical Intermediate

A critical protected precursor and synthetic building block utilized in the industrially viable multi-step synthesis of Droxidopa (L-threo-DOPS), an orally active synthetic precursor of norepinephrine used to treat neurogenic orthostatic hypotension and symptoms associated with Parkinson's disease

Analytical Reference Standard

A highly characterized reference material used for analytical method development, method validation, and quality control in pharmaceutical manufacturing to ensure the precision and reliability of Droxidopa production.

(2S,3R)-3-(3,4-bis(benzyloxy)phenyl)-2-amino-3-hydroxypropanoic acid FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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