21-DEACETOXY-DEFLAZACORT (D5/D8)

CAS Number: 13649-88-2

Molecular Formula: C23H29NO4

About 21-DEACETOXY-DEFLAZACORT (D5/D8)

21-Deacetoxy Deflazacort (CAS 13649-88-2) serves as a critical structural precursor in the synthesis of specialized glucocorticoids, and as a bulk chemical supplier, we see increasing domestic demand for high purity fine chemicals that support the development of therapies for rare genetic disorders like Duchenne Muscul...

21-DEACETOXY-DEFLAZACORT (D5/D8) Specifications

CAS Number

13649-88-2

Molecular Formula

C23H29NO4

Molecular Weight

383.49 g/mol

IUPAC Name

(1S,2S,4R,8S,9S,11S,12S,13R)-8-acetyl-11-hydroxy-6,9,13-trimethyl-5-oxa-7-azapentacyclo[10.8.0.02,9.04,8.013,18]icosa-6,14,17-trien-16-one

Canonical SMILES

CC1=N[C@@]2([C@H](O1)C[C@@H]3[C@@]2(C[C@@H]([C@H]4[C@H]3CCC5=CC\(=O\)C=C[C@]45C)O)C)C(=O)C

InChI Key

WQUXBQVUVGNOKK-AAZVSSJSSA-N

CAS Number

13649-88-2

Molecular Formula

C23H29NO4

Molecular Weight

383.49 g/mol

IUPAC Name

(1S,2S,4R,8S,9S,11S,12S,13R)-8-acetyl-11-hydroxy-6,9,13-trimethyl-5-oxa-7-azapentacyclo[10.8.0.02,9.04,8.013,18]icosa-6,14,17-trien-16-one

Canonical SMILES

CC1=N[C@@]2([C@H](O1)C[C@@H]3[C@@]2(C[C@@H]([C@H]4[C@H]3CCC5=CC\(=O\)C=C[C@]45C)O)C)C(=O)C

InChI Key

WQUXBQVUVGNOKK-AAZVSSJSSA-N

Molecular Weight

383.49 g/mol

Physical appearance

White to almost white powder to crystal

Pharmaceutical Intermediate

An intermediate of Deflazacort, a systemic corticosteroid used for the treatment of Duchenne muscular dystrophy (DMD)

Glucocorticoid Precursor

A dehydrogenated derivative of Deflazacort that acts as an inactive precursor rapidly converted to the active metabolite 21-desacetyldeflazacort

Organic Synthesis Building Block

A functionalized steroid derivative used in research and development for the synthesis of bioactive molecules with anti-inflammatory and immunosuppressant properties

Analytical Reference Standard

A chemical building block used in laboratory settings for the qualitative and quantitative analysis of corticosteroids and their metabolic derivatives.