2-Methylpyridine (CAS NO : 109-06-8)

2-Methylpyridine (CAS No: 109-06-8), commonly known as 2-picoline, is a critical heterocyclic intermediate extensively used across the U.S. chemical manufacturing sector to produce 2-vinylpyridine for the rubber industry and the nitrogen fertilizer synergist nitrapyrin. The compound’s reactive methyl group is essential for synthesizing high-demand agrochemicals, such as the herbicide 4-amino-3,5,6-trichloropyridine, and vital pharmaceutical agents including amprolium, picoplatin, and the organophosphorus antidote pralidoxime chloride. While traditionally sourced from coal tar or gas-phase reactions of acetaldehyde and ammonia, current industrial production in the United States favors cobalt-catalyzed trimerization of acetonitrile and acetylene, achieving high regioselectivity and yields exceeding 90%. As a leading 2-Methylpyridine supplier offering 99.9% purity, we provide American domestic partners with dependable supply, consistent quality, and comprehensive regulatory documentation, including 2-Methylpyridine CoA and TDS for all grades. Beyond chemical supply, we support clients throughout the product lifecycle, from initial route scouting and process development to scale-up and commercial-scale manufacturing. Our dedicated teams also provide expertise in GMP-compliant quality assurance, EPA and TSCA regulatory filings, and streamlined global supply chain logistics.