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2-Iodoacetamide

2-Iodoacetamide

CAS Number: 144-48-9

Molecular Formula: C2H4INO

About 2-Iodoacetamide

2-Iodoacetamide (CAS 144-48-9) remains a cornerstone alkylating agent for cysteine residue modification in the United States proteomics sector, where high purity fine chemicals are essential for preventing disulfide bond reformation during mass spectrometry-based peptide mapping. Alpha-iodoacetamide is increasingly int...

2-Iodoacetamide Specifications

CAS Number

144-48-9

Molecular Formula

C2H4INO

Molecular Weight

184.96 g/mol

IUPAC Name

2-iodoacetamide

Canonical SMILES

NC(=O)CI

InChI Key

PGLTVOMIXTUURA-UHFFFAOYSA-N

CAS Number

144-48-9

Molecular Formula

C2H4INO

Molecular Weight

184.96 g/mol

IUPAC Name

2-iodoacetamide

Canonical SMILES

NC(=O)CI

InChI Key

PGLTVOMIXTUURA-UHFFFAOYSA-N

Molecular Weight

184.96 g/mol

Cysteine Alkylating Agent

A commonly used reagent for the alkylation of cysteine residues during protein sample preparation for proteomics and de novo peptide sequencing to prevent the formation of disulfide bonds

Enzyme Inhibitor

An irreversible inhibitor of various enzymes, including cysteine peptidases and deubiquitinase enzymes (DUBs), by covalently binding to the catalytic cysteine residue at the active site

Glycolysis Inhibitor

A chemical agent used in metabolic studies to inhibit glycolysis by inactivating the enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

Organic Synthesis Building Block

A functionalized organic compound used as an electrophile for the covalent modification of nucleophilic residues on proteins such as methionine and histidine in biochemical research.

2-Iodoacetamide FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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