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2-(Chloromethyl)-4-methylquinazoline (CAS 109113-72-6) serves as a critical structural component in the North American API intermediates market, primarily as the key building block for the synthesis of Linagliptin and its associated impurities where a Pharma/API purity 99% is mandatory to satisfy US FDA and ICH regulatory guidelines. Linagliptin Intermediate A has seen a surge in domestic demand as US-based CDMOs expand their custom synthesis services to offer high purity fine chemicals that mitigate the risks of global sourcing shifts and ensure supply chain resilience for type 2 diabetes therapeutic pipelines. Linagliptin INT3 is also utilized at a general industry purity 98% in specialized material science and agrochemical applications, where its quinazoline scaffold acts as a versatile building block for developing advanced heterocyclic polymers and targeted pesticides, necessitating a reliable bulk chemical supplier capable of providing stringent quality assurance and technical documentation. We are an established 2-(Chloromethyl)-4-methylquinazoline intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting 2-(Chloromethyl)-4-methylquinazoline COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities
2-(Chloromethyl)-4-methylquinazoline (CAS 109113-72-6) serves as a critical structural component in the North American API intermediates market, primarily as the key building block for the synthesis of Linagliptin and its associated impurities where a Pharma/API purity 99% is mandatory to satisfy US FDA and ICH regulatory guidelines. Linagliptin Intermediate A has seen a surge in domestic demand as US-based CDMOs expand their custom synthesis services to offer high purity fine chemicals that mitigate the risks of global sourcing shifts and ensure supply chain resilience for type 2 diabetes therapeutic pipelines. Linagliptin INT3 is also utilized at a general industry purity 98% in specialize...
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
P203, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P284, P301+P310+P330, P301+P317, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P304+P340+P310, P305+P351+P338, P305+P351+P338+P310, P305+P354+P338, P310, P317, P318, P321, P330, P333+P317, P362+P364, P363, P391, P403+P233, P405, and P501
Acute Tox. 4 (100%)
Skin Sens. 1A (100%)
A building block used for the preparation of Linagliptin and its related substances, which are utilized as dipeptidyl peptidase-4 (DPP-4) inhibitors in the treatment of type 2 diabetes
A versatile heterocyclic intermediate used in the development of novel therapeutic agents, particularly in cancer research for the synthesis of 4-anilinoquinazoline derivatives and other biologically active compounds
A functionalized quinazoline derivative explored in the formulation of specialized herbicides and pesticides to target specific plant pathways and improve crop yields
A high-purity chemical used as a reference material for identifying and quantifying impurities in pharmaceutical manufacturing and quality control processes.
2-(Chloromethyl)-4-methylquinazoline is a heterocyclic building block and versatile chemical intermediate primarily used in the synthesis of pharmaceuticals like Linagliptin for type 2 diabetes and in the development of anticancer agents
This compound is widely utilized in the pharmaceutical, agrochemical, and material science industries for drug discovery, herbicide development, and the creation of specialized polymers
It is a solid powder or crystal, typically used in organic synthesis protocols and compatible with liquid-phase reactions involving nucleophilic substitution
Standard specifications include CAS number 109113-72-6, a purity of ≥98%, and available documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
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