

2,4-Thiazolidinedione (CAS 2295-31-0) is a foundational heterocyclic building block in the US API intermediates market, primarily utilized for the synthesis of glitazone-class antidiabetics and emerging oncology therapeutics where Pharma/API purity 99% is mandatory for FDA-compliant manufacturing. Thiazolidine-2,4-dione serves as a high purity fine chemical integral to custom synthesis services provided by North American CDMOs who are shifting toward domestic sourcing to ensure supply chain transparency and rigorous quality control. TZD is also utilized as a versatile scaffold in general industry applications at a General Industry purity 98%, where its unique reactivity is leveraged by specialized bulk chemical suppliers for the development of novel agrochemicals and functional materials. We are an established 2,4-Thiazolidinedione intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting 2,4-Thiazolidinedione COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities


2,4-Thiazolidinedione (CAS 2295-31-0) is a foundational heterocyclic building block in the US API intermediates market, primarily utilized for the synthesis of glitazone-class antidiabetics and emerging oncology therapeutics where Pharma/API purity 99% is mandatory for FDA-compliant manufacturing. Thiazolidine-2,4-dione serves as a high purity fine chemical integral to custom synthesis services provided by North American CDMOs who are shifting toward domestic sourcing to ensure supply chain transparency and rigorous quality control. TZD is also utilized as a versatile scaffold in general industry applications at a General Industry purity 98%, where its unique reactivity is leveraged by speci...
Pharmaceutical
Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
P261, P264+P265, P272, P280, P302+P352, P305+P351+P338, P321, P333+P317, P337+P317, P362+P364, and P501
Skin Sens. 1 (96.4%)
Eye Irrit. 2A (100%)
A versatile scaffold and key building block used in the synthesis of various bioactive derivatives and active pharmaceutical ingredients, including FDA-approved glitazones like pioglitazone and rosiglitazone
A primary therapeutic pharmacophore that acts as a PPAR-gamma agonist to increase insulin sensitivity, enhance glucose uptake, and manage type 2 diabetes mellitus
A privileged sulfur-containing heterocyclic motif utilized in medicinal chemistry research to develop compounds with antimicrobial, anticancer, anti-inflammatory, and antioxidant activities
A functional agent reported for use as a corrosion inhibitor for steel in acidic environments and as a brightener within the electroplating industry.
2,4-Thiazolidinedione, also known as TZD, is a heterocyclic compound that serves as a privileged scaffold in medicinal chemistry, primarily used as an insulin-sensitizing agent for the management of type 2 diabetes mellitus
This compound is predominantly used in the pharmaceutical and agrochemical industries for the development of antidiabetic drugs, as well as antimicrobial, anti-inflammatory, and antioxidant agents
It is compatible with oral tablet formulations, often as monotherapy or in combination with other agents like metformin, and is also utilized in various liquid-phase synthetic protocols
Standard analytical specifications include CAS number 2295-31-0, high purity levels, and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
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