Search through
2-(4-Fluorophenyl)thiophene (CAS 58861-48-6) acts as a pivotal building block within the high purity fine chemicals sector, where it is primarily utilized as a critical intermediate for the synthesis of Canagliflozin, a leading SGLT2 inhibitor for type 2 diabetes treatment. Thiophene, 2-(4-fluorophenyl)- serves the domestic API intermediates market by providing a robust synthetic precursor that meets the stringent Pharma/API purity 99% threshold required for FDA-regulated therapeutic formulations. The growing reliance on custom synthesis services in the United States highlights a strategic shift toward domestic CDMO growth, ensuring that any leading bulk chemical supplier can mitigate supply chain risks while maintaining rigorous regulatory compliance and analytical precision. We are an established 2-(4-Fluorophenyl)thiophene intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting 2-(4-Fluorophenyl)thiophene COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities
2-(4-Fluorophenyl)thiophene (CAS 58861-48-6) acts as a pivotal building block within the high purity fine chemicals sector, where it is primarily utilized as a critical intermediate for the synthesis of Canagliflozin, a leading SGLT2 inhibitor for type 2 diabetes treatment. Thiophene, 2-(4-fluorophenyl)- serves the domestic API intermediates market by providing a robust synthetic precursor that meets the stringent Pharma/API purity 99% threshold required for FDA-regulated therapeutic formulations. The growing reliance on custom synthesis services in the United States highlights a strategic shift toward domestic CDMO growth, ensuring that any leading bulk chemical supplier can mitigate supply...
.3d8f8f41.svg)
Pharmaceutical
.3556d45a.svg)
Pharmaceutical Actives & Precursors
Intermediates & Precursors
.7767eb0f.png)
Chemical Properties & Specifications
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Acute Tox. 4 (100%)
Skin Irrit. 2 (50%)
A key synthetic building block primarily utilized in the production of the SGLT2 inhibitor canagliflozin for the treatment of type 2 diabetes
A fluorinated thiophene derivative employed in cross-coupling reactions to develop complex heterocyclic molecules with potential pharmacological properties
A specialized material used in medicinal chemistry to study structure-activity relationships, particularly regarding the influence of fluorine on metabolic stability and lipophilicity.
2-(4-Fluorophenyl)thiophene is a thiophene derivative that serves as a crucial building block and key pharmaceutical intermediate, most notably used in the synthesis of the SGLT2 inhibitor Canagliflozin for treating type 2 diabetes
This compound is primarily used in the pharmaceutical and agrochemical industries, as well as in material science for developing advanced polymers and specialty coatings
It is a white to light orange solid at room temperature that becomes liquid upon heating and is soluble in organic solvents like methanol, dichloromethane, and ethyl acetate
Standard specifications include CAS number 58861-48-6, a purity of typically 95% or higher, melting point of 51-55°C, and available documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
Description : P-Nitrobenzoyl Chloride (CAS 122-04-3) is a critical building block in the API intermediates market,...
