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16-ALFA-METHYL-9,11-EPOXIDE(8DM)

16-ALFA-METHYL-9,11-EPOXIDE(8DM)

CAS Number: 24916-90-3

Molecular Formula: C22H28O5

About 16-ALFA-METHYL-9,11-EPOXIDE(8DM)

16-Alpha-Methyl-9,11-Epoxide (CAS 24916-90-3) is a critical steroid intermediate utilized extensively by US-based CDMOs for the synthesis of high-potency corticosteroids like dexamethasone and mometasone furoate, requiring Pharma/API purity 99% to ensure the efficacy of finished oral and injectable formulations in a la...

16-ALFA-METHYL-9,11-EPOXIDE(8DM) Specifications

CAS Number

24916-90-3

Molecular Formula

C22H28O5

Molecular Weight

372.46 g/mol

IUPAC Name

(9β,11β,16α)-9,11-epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione

Canonical SMILES

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4([C@]35[C@@H](O5)C[C@@]2([C@]1(C(=O)CO)O)C)C

InChI Key

GBDXNHBVYAMODG-QDBZYVRYSA-N

PubChem CID

11143226.0

CAS Number

24916-90-3

Molecular Formula

C22H28O5

Molecular Weight

372.46 g/mol

IUPAC Name

(9β,11β,16α)-9,11-epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione

Canonical SMILES

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4([C@]35[C@@H](O5)C[C@@]2([C@]1(C(=O)CO)O)C)C

InChI Key

GBDXNHBVYAMODG-QDBZYVRYSA-N

PubChem CID

11143226.0

Molecular Weight

372.46 g/mol

Physical appearance

White to pale yellow solid

Pharmaceutical Intermediate

A vital steroid medicine intermediate used as a key precursor in the synthesis of corticosteroids such as dexamethasone, betamethasone, and mometasone furoate

Immunosuppressive Agent

An active raw material utilized in medical research to develop treatments for modulating the immune system and managing autoimmune diseases

Chemical Research Building Block

A high-purity crystalline compound employed in academic and industrial laboratories for the development of complex molecules and pharmaceutical impurities.

16-ALFA-METHYL-9,11-EPOXIDE(8DM) FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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