1-Stearoyl-lysophosphatidylcholine

CAS Number: 19420-57-6

Molecular Formula: C26H54NO7P

About 1-Stearoyl-lysophosphatidylcholine

1-Stearoyl-2-hydroxy-sn-glycero-3-PC (CAS 19420-57-6) is a critical signaling lipid and surfactant increasingly utilized by high purity fine chemicals producers for the development of advanced liposomal drug delivery systems and mRNA-based therapeutics. 18:0 Lyso-PC serves as a vital biochemical standard and functional...

1-Stearoyl-lysophosphatidylcholine Specifications

CAS Number

19420-57-6

Molecular Formula

C26H54NO7P

Molecular Weight

523.68 g/mol

IUPAC Name

[(2R)-2-hydroxy-3-octadecanoyloxypropyl] 2-trimethylazaniumylethyl phosphate

Canonical SMILES

CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)O

InChI Key

IHNKQIMGVNPMTC-RUZDIDTESA-N

CAS Number

19420-57-6

Molecular Formula

C26H54NO7P

Molecular Weight

523.68 g/mol

IUPAC Name

[(2R)-2-hydroxy-3-octadecanoyloxypropyl] 2-trimethylazaniumylethyl phosphate

Canonical SMILES

CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)O

InChI Key

IHNKQIMGVNPMTC-RUZDIDTESA-N

Molecular Weight

523.68 g/mol

Drug Delivery System Component

A critical phospholipid used in the development of transdermal delivery devices, liposomes, and micelles to encapsulate and deliver therapeutic agents effectively

Anticancer Research Tool

A bioactive lysophosphatidylcholine that induces apoptosis in chronic myelogenous leukemia (CML) K562 cells by inhibiting HDAC3 activity and STAT3 phosphorylation

Immunomodulatory Agent

A signaling lipid that enhances macrophage phagocytosis via the AMPK/p38 MAPK pathway and suppresses the release of proinflammatory cytokines like HMGB1 in sepsis models

Model Membrane Component

A surfactant-like molecule used to study membrane curvature, lipid-protein interactions, and bilayer dynamics due to its ability to induce positive curvature and influence vesicle stability

Calibration Standard

A high-purity lipid used in lipidomic and metabolomic profiling for the quantification of lysophospholipids and monitoring disease biomarkers via mass spectrometry.