1-Hydroxybenzotriazole Anhydrous

CAS Number: 2592-95-2

Molecular Formula: C6H5N3O

About 1-Hydroxybenzotriazole Anhydrous

1-Hydroxybenzotriazole Anhydrous (CAS 2592-95-2) serves as a gold-standard peptide coupling additive in the United States, essential for suppressing racemization and enhancing amide bond formation efficiency in high purity fine chemicals production. HOBt (1-Hydroxybenzotriazole) is witnessing a surge in domestic demand...

1-Hydroxybenzotriazole Anhydrous Specifications

CAS Number

2592-95-2

Molecular Formula

C6H5N3O

Molecular Weight

135.12 g/mol

IUPAC Name

1-hydroxybenzotriazole

Canonical SMILES

C1=CC=C2C(=C1)N=NN2O

InChI Key

ASOKPJOREAFHNY-UHFFFAOYSA-N

EINECS Number

219-989-7

MDL Number

MFCD00005805

HSN No

29339100

CAS Number

2592-95-2

Molecular Formula

C6H5N3O

Molecular Weight

135.12 g/mol

IUPAC Name

1-hydroxybenzotriazole

Canonical SMILES

C1=CC=C2C(=C1)N=NN2O

InChI Key

ASOKPJOREAFHNY-UHFFFAOYSA-N

EINECS Number

219-989-7

MDL Number

MFCD00005805

HSN No

29339100

Molecular Weight

135.12 g/mol

Physical appearance

White to off-white powder or crystals

Boiling Point

149-150 °C

Flash Point

95 °C

Density

1 g/cm3

Precautionary Statement Codes

P210, P230, P240, P250, P280, P370+P380, P372, P373, P401, and P501

Hazard Classes and Categories

Expl. 1.3 (49.2%) Flam. Sol. 2 (49.2%)

Peptide Coupling Reagent

A common nucleophilic additive used in combination with carbodiimides to enhance the efficiency of amide bond formation and suppress racemization during peptide synthesis

Racemization Suppressor

A critical reagent employed in both solution and solid-phase peptide synthesis to maintain the chiral integrity of amino acid residues during coupling reactions

Organic Synthesis Intermediate

A versatile reagent used to prepare activated esters and synthesize various nitrogen-containing heterocycles such as oxadiazoles

Lignin Degradation Mediator

A specialized chemical used in enzymatic systems, particularly with laccase, to facilitate the oxidation and depolymerization of nonphenolic lignin in pulp bleaching processes.