

1-Bromo-2-methylpropane (CAS 78-77-3) is a vital alkylating agent in the American fine chemical synthesis market, highly valued by US-based researchers for its efficiency in introducing the isobutyl group into complex molecular structures. It is a critical component in the development of pharmaceutical intermediates like isobutylboronic acid, a key building block for the production of bortezomib. With superior leaving group capabilities compared to chlorinated alternatives, this compound enables more effective SN2 and E2 reaction pathways, allowing domestic drug development professionals to optimize synthetic yields and reaction kinetics. Its applications also extend across the US polymer and agrochemical sectors, where its high 99% purity supports the creation of high-performance materials and specialized crop protection solutions. As a leading 1-Bromo-2-methylpropane supplier, we provide reliable domestic supply, consistent quality, and comprehensive regulatory documentation, including CoA and TDS for all grades. Our American-based teams support partners through the complete product lifecycle, from initial route scouting and process development to analytical method validation, scale-up, and full-scale commercial manufacturing. We also offer expert assistance with GMP-compliant quality assurance, regulatory filings, and global supply chain logistics coordination.


1-Bromo-2-methylpropane (CAS 78-77-3) is a vital alkylating agent in the American fine chemical synthesis market, highly valued by US-based researchers for its efficiency in introducing the isobutyl group into complex molecular structures. It is a critical component in the development of pharmaceutical intermediates like isobutylboronic acid, a key building block for the production of bortezomib. With superior leaving group capabilities compared to chlorinated alternatives, this compound enables more effective SN2 and E2 reaction pathways, allowing domestic drug development professionals to optimize synthetic yields and reaction kinetics. Its applications also extend across the US polymer an...
Elemental Derivatives
Bromine
Bromo Alkyls & Alkenes
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Chemical Properties & Specifications
A versatile building block and alkyl halide used for the creation of complex molecules, including pharmaceuticals and agrochemicals
A reagent primarily used to introduce the isobutyl group in organic synthesis, such as the preparation of 1-ethyl-1,3-isobutylimidazolium bromide
A key precursor used to synthesize isobutylbenzene for the production of Ibuprofen and isobutylboronic acid for the synthesis of Bortezomib
A medium used in various laboratory chemical reactions to enhance reaction rates and yields
An important intermediate used in the manufacturing of plastics, coatings, dyes, and specialty chemicals like surfactants or lubricants
1-Bromo-2-methylpropane, also known as isobutyl bromide, is a halogenated alkane that serves as a versatile building block and synthetic reagent in organic chemistry. It is primarily used to introduce isobutyl groups in the synthesis of various complex molecules, including pharmaceuticals and agrochemicals
This compound is widely utilized in the pharmaceutical, agrochemical, and specialty chemical industries, as well as in research laboratories for studying reaction mechanisms and developing plastics and coatings
It is a colorless liquid that is slightly soluble in water but miscible with organic solvents like ethanol and ether, making it suitable for liquid-phase synthesis and as a solvent in laboratory settings
Standard specifications include CAS number 78-77-3, high purity levels (typically ≥97% or ≥99% by GC), and technical documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a generally accepted MOQ starting from 100 kgs, though lead times for international customers vary based on shipping destination and grade.
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