Desvenlafaxine Succinate

CAS Number: 93413-62-8

Molecular Formula: C16H25NO2

THERAPEUTIC CATEGORY : Antidepressant(FDA) Approved for major depressive disorder in adultsEU approved in Spain (2012) and Germany (2022)Extended-Release FormulationMinimal CYP450 InteractionUNII Code: NG99554ANWCHEMBL1118

About Desvenlafaxine Succinate

Desvenlafaxine Succinate is a serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant used to treat major depressive disorder (MDD) in adults. It is the active metabolite of venlafaxine, another antidepressant, and works by increasing the levels of serotonin and norepinephrine in the brain, which helps regula...

Desvenlafaxine Succinate Specifications

CAS Number

93413-62-8

Molecular Formula

C16H25NO2

Molecular Weight

275.38 g/mol

IUPAC Name

RS)-4-[2-Dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenol

Canonical SMILES

OC2(C(c1ccc(O)cc1)CN(C)C)CCCCC2

InChI Key

KYYIDSXMWOZKMP-UHFFFAOYSA-N

InChI

InChI=1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3

UNII Code

NG99554ANW

MDL Number

MFCD00871934

CAS Number

93413-62-8

Molecular Formula

C16H25NO2

Molecular Weight

275.38 g/mol

IUPAC Name

RS)-4-[2-Dimethylamino-1-(1-hydroxycyclohexyl)ethyl]phenol

Canonical SMILES

OC2(C(c1ccc(O)cc1)CN(C)C)CCCCC2

InChI Key

KYYIDSXMWOZKMP-UHFFFAOYSA-N

InChI

InChI=1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3

UNII Code

NG99554ANW

MDL Number

MFCD00871934

Molecular Weight

275.38 g/mol

Solubility in Water

Soluble in water

Solubility in Organic Solvents

Soluble in methanol, ethanol

Appearance

White to off-white crystalline powder

Odor

Odorless

Shelf Life

2 years

Hazard Statements

H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.

Precautionary Statements

P261: Avoid breathing dust/fume/gas/mist/vapors/spray. P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear protective gloves/eye protection/face protection. P302+P352: IF ON SKIN: Wash with plenty of soap and water. P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor if you feel unwell. P321: Specific treatment (see on this label). P332+P313: If skin irritation occurs: Get medical advice/attention. P337+P313: If eye irritation persists: Get medical advice/attention. P362: Take off contaminated clothing and wash before reuse. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container in accordance with local/regional/national/international regulations.

Major Depressive Disorder (MDD)

Desvenlafaxine Succinate is prescribed for the treatment of MDD in adults. It helps alleviate symptoms such as persistent feelings of sadness, loss of interest in daily activities, and fatigue.

End Use Pharmaceutical Formulations

Incorporated into oral dosage forms, specifically extended-release tablets, to ensure consistent delivery of the medication over time. Common strengths include 25 mg, 50 mg, and 100 mg tablets.