1-Hydroxybenzotriazole Anhydrous

CAS Number: 2592-95-2

Molecular Formula: C6H5N3O

About 1-Hydroxybenzotriazole Anhydrous

1-Hydroxybenzotriazole Anhydrous (CAS 2592-95-2) acts as a pivotal coupling reagent within the API intermediates market, essential for suppressing racemization during peptide synthesis and complex amide bond formations. HOBt Anhydrous is increasingly favored by CDMOs providing custom synthesis services to ensure high-y...

1-Hydroxybenzotriazole Anhydrous Specifications

CAS Number

2592-95-2

Molecular Formula

C6H5N3O

Molecular Weight

135.12 g/mol

IUPAC Name

1-hydroxybenzotriazole

Canonical SMILES

C1=CC=C2C(=C1)N=NN2O

InChI Key

ASOKPJOREAFHNY-UHFFFAOYSA-N

EINECS Number

219-989-7

MDL Number

MFCD00005805

HSN No

29339100

CAS Number

2592-95-2

Molecular Formula

C6H5N3O

Molecular Weight

135.12 g/mol

IUPAC Name

1-hydroxybenzotriazole

Canonical SMILES

C1=CC=C2C(=C1)N=NN2O

InChI Key

ASOKPJOREAFHNY-UHFFFAOYSA-N

EINECS Number

219-989-7

MDL Number

MFCD00005805

HSN No

29339100

Molecular Weight

135.12 g/mol

Physical appearance

White to off-white powder or crystals

Boiling Point

149-150 °C

Flash Point

95 °C

Density

1 g/cm3

Precautionary Statement Codes

P210, P230, P240, P250, P280, P370+P380, P372, P373, P401, and P501

Hazard Classes and Categories

Expl. 1.3 (49.2%) Flam. Sol. 2 (49.2%)

Peptide Coupling Reagent

A common nucleophilic additive used in combination with carbodiimides to enhance the efficiency of amide bond formation and suppress racemization during peptide synthesis

Racemization Suppressor

A critical reagent employed in both solution and solid-phase peptide synthesis to maintain the chiral integrity of amino acid residues during coupling reactions

Organic Synthesis Intermediate

A versatile reagent used to prepare activated esters and synthesize various nitrogen-containing heterocycles such as oxadiazoles

Lignin Degradation Mediator

A specialized chemical used in enzymatic systems, particularly with laccase, to facilitate the oxidation and depolymerization of nonphenolic lignin in pulp bleaching processes.