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Sodium cyanoborohydride (CAS NO : 25895-60-7)

Sodium cyanoborohydride (CAS No: 25895-60-7) serves as a pivotal, highly selective reducing agent in the global pharmaceutical and fine chemical industries, particularly valued for its superior stability in acidic media and its critical role in the reductive amination of aldehydes and ketones during the synthesis of complex active pharmaceutical ingredients (APIs). The market is currently seeing a significant shift towards more rigorous analytical control strategies, such as chromatographic assays, to monitor and mitigate residual free cyanide impurities that can lead to undesired side products in bioconjugation processes for proteins and peptides. Furthermore, while the broader borohydride sector is projected to reach USD 376 million by 2032 with a CAGR of 6.6%, sodium cyanoborohydride maintains a specialised niche for hindered-ketone API synthesis due to its documented high yields and selectivity compared to alternative reducing agents, despite increasing pricing pressures from raw material fluctuations. As globally established Sodium cyanoborohydride supplier with 97% min. purity %. We ensure dependable supply, consistent quality, and complete regulatory documentation, including Sodium cyanoborohydride CoA and Sodium cyanoborohydride TDS across all grades. Beyond supply, we support partners through the entire product lifecycle from route scouting, process and formulation development, and analytical method development to scale-up, process optimisation, and pilot-to-commercial manufacturing. Our teams also assist with GMP-compliant quality assurance, regulatory documentation, and global supply chain and logistics coordination.

Sodium cyanoborohydride

Sodium cyanoborohydride (CAS No: 25895-60-7) serves as a pivotal, highly selective reducing agent in the global pharmaceutical and fine chemical industries, particularly valued for its superior stability in acidic media and its critical role in the reductive amination of aldehydes and ketones during the synthesis of complex active pharmaceutical ingredients (APIs). The market is currently seeing a significant shift towards more rigorous analytical control strategies, such as chromatographic assays, to monitor and mitigate residual free cyanide impurities that can lead to undesired side products in bioconjugation processes for proteins and peptides. Furthermore, while the broader borohydride ...

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Chemical Properties & Specifications

Applications of Sodium cyanoborohydride

Reducing Agent

A mild and selective reducing agent used for the reduction of imines, carbonyls, oximes, and enamines in organic synthesis

Organic Synthesis

A reagent for the reductive amination of aldehydes and ketones to produce primary, secondary, and tertiary amines

Pharmaceutical Synthesis

A chemical intermediate used in the production of pharmaceuticals and fine chemicals due to its ability to facilitate reactions under mild conditions

Bioconjugation

A reagent employed in the bioconjugation of proteins and peptides and the modification of nucleic acids in DNA and RNA research

Polymer Chemistry

A component used in the preparation of polymeric materials such as hydrogels for drug delivery systems

Environmental Remediation

A treatment agent used for the reduction of harmful substances in contaminated water

Have Questions About Sodium cyanoborohydride?
We've Got Answers.

Sodium cyanoborohydride, also known as sodium cyanotrihydridoborate, is a mild and selective reducing agent with the formula Na[BH3(CN)] used in organic synthesis for the chemical reduction of imines, carbonyls, aldehydes, and ketones

This compound is widely used in the pharmaceutical, agrochemical, polymer, and fine chemical industries for applications including bioconjugation of proteins, drug development, and the production of specialty chemicals

Sodium cyanoborohydride is soluble in aprotic solvents and remains stable under acidic conditions, making it suitable for liquid-phase synthesis protocols and the preparation of materials like hydrogels

Provided specifications include CAS number 25895-60-7, molecular weight 62.84, molecular formula BCH3NNa, and documentation such as COA, TDS, impurity reports, and regulatory compliance documents

Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time

The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.

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