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Zofran (Ondansetron hydrochloride dihydrate) (CAS NO : 103639-04-9)

Ondansetron Hydrochloride Dihydrate (Zensana) is a selective serotonin 5-HT3 receptor antagonist used as an antiemetic for preventing nausea and vomiting associated with chemotherapy, radiotherapy, and postoperative conditions. It works by blocking serotonin receptors in the central nervous system and gastrointestinal tract. Also referred to as (GR-38032F, and Ondansetron HCl Dihydrate or Ondansetron (hydrochloride dihydrate) by Ondansetron api manufacturers, it demonstrates high potency, oral bioavailability, and metabolic stability. We are the trusted Ondansetron Hydrochloride Dihydrate supplier worldwide, ensuring reliable lead times and consistent API quality for pharmaceutical manufacturing and clinical research.

Zofran (Ondansetron hydrochloride dihydrate)

Ondansetron Hydrochloride Dihydrate (Zensana) is a selective serotonin 5-HT3 receptor antagonist used as an antiemetic for preventing nausea and vomiting associated with chemotherapy, radiotherapy, and postoperative conditions. It works by blocking serotonin receptors in the central nervous system and gastrointestinal tract. Also referred to as (GR-38032F, and Ondansetron HCl Dihydrate or Ondansetron (hydrochloride dihydrate) by Ondansetron api manufacturers, it demonstrates high potency, oral bioavailability, and metabolic stability. We are the trusted Ondansetron Hydrochloride Dihydrate supplier worldwide, ensuring reliable lead times and consistent API quality for pharmaceutical manufactu...

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Chemical Properties & Specifications

Applications of Zofran (Ondansetron hydrochloride dihydrate)

Pharmaceutical Use

Prevention and treatment of nausea and vomiting in (Cancer chemotherapy), radiotherapy (Radiation therapy), and treat postoperative surgery (Postoperative care)

Mechanism of Action

Selective 5-HT3 receptor antagonism reduces central and peripheral nausea signaling

Oral and Injectable Formulations

Supports tablets, oral disintegrating tablets, and injectable dosage forms

Metabolic Stability

Resistant to rapid metabolism, providing consistent therapeutic effects

R & D

Preferred in pharmacokinetic studies, 5-HT3 receptor studies, and preclinical antiemetic research

B2B Features

Suitable for API supply to pharmaceutical manufacturers, contract formulation & clinical research

Have Questions About Zofran (Ondansetron hydrochloride dihydrate)?
We've Got Answers.

Used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, and post-surgery.

Blocks 5-HT3 serotonin receptors in the CNS and gastrointestinal tract to reduce nausea signaling.

Typically ≥99% by HPLC assay.

Pharmaceutical API manufacturers, contract research organizations, and formulation development companies.

Handle in controlled environments using protective gloves and eyewear to prevent contamination.

Tablets, oral disintegrating tablets, and injectable formulations.

Yes, Universally used in preclinical and clinical pharmacology studies for antiemetic research.

Available in kilogram quantities, with bulk supply options for pharmaceutical manufacturing.

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