Vonoprazan Fumarate

CAS Number: 881681-01-2

Molecular Formula: C21H20FN3O6S

Purity: Vonoprazan Fumarate 98% purity

About Vonoprazan Fumarate

Vonoprazan Fumarate (CAS 881681-01-2) acts as a premier potassium-competitive acid blocker (P-CAB), representing a transformative shift in the API intermediates market for treating acid-related disorders like GERD and H. pylori infections due to its superior clinical profile compared to traditional proton pump inhibito...

Synonyms

1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
TAK 438
TAK-438
TAK438
Vonoprazan

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Vonoprazan Fumarate Specifications

CAS Number

881681-01-2

Molecular Formula

C21H20FN3O6S

Molecular Weight

461.47 g/mol

IUPAC Name

(E)-but-2-enedioic acid;1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine

Canonical SMILES

CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=CC(=O)O)C(=O)O

InChI Key

ROGSHYHKHPCCJW-WLHGVMLRSA-N

InChI

InChI=1S/C17H16FN3O2S.C4H4O4/c1-19-10-13-9-17(15-6-2-3-7-16(15)18)21(12-13)24(22,23)14-5-4-8-20-11-14;5-3(6)1-2-4(7)8/h2-9,11-12,19H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

HSN No

29339990

CAS Number

881681-01-2

Molecular Formula

C21H20FN3O6S

Molecular Weight

461.47 g/mol

IUPAC Name

(E)-but-2-enedioic acid;1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine

Canonical SMILES

CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=CC(=O)O)C(=O)O

InChI Key

ROGSHYHKHPCCJW-WLHGVMLRSA-N

InChI

InChI=1S/C17H16FN3O2S.C4H4O4/c1-19-10-13-9-17(15-6-2-3-7-16(15)18)21(12-13)24(22,23)14-5-4-8-20-11-14;5-3(6)1-2-4(7)8/h2-9,11-12,19H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

HSN No

29339990

Molecular Weight

461.47 g/mol

Purity

Vonoprazan Fumarate 98% purity

Gastrointestinal Therapeutic Agent

A first-in-class potassium-competitive acid blocker (P-CAB) used for the healing and maintenance of all grades of erosive esophagitis and the relief of associated heartburn in adults

GERD Treatment

An oral medication indicated for the relief of heartburn associated with non-erosive gastroesophageal reflux disease (GERD)

H. pylori Eradication Adjunct

A potent acid suppressant used in combination with antibiotics such as amoxicillin and clarithromycin to treat Helicobacter pylori infections and reduce the risk of duodenal ulcer recurrence

Pharmaceutical Intermediate

A high-purity active pharmaceutical ingredient (API) and building block utilized in the synthesis of advanced gastrointestinal therapies for treating gastroduodenal ulcers and acid-related diseases.