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Trimethylsulfoxonium Bromide (TMSOBR) (CAS NO : 25596-24-1)

Trimethylsulfoxonium Bromide (CAS No: 25596-24-1) is a vital sulfoxonium salt that serves as an indispensable reagent in modern organic synthesis, particularly through the Corey-Chaykovsky reaction to facilitate the stereoselective construction of epoxides, cyclopropanes, and aziridines. In the global pharmaceutical sector, it functions as a critical synthetic building block for producing active pharmaceutical ingredients (APIs) such as methylcobalamin and various antiviral or antifungal agents, where its role in generating dimethylsulfoxonium methylide allows for the efficient formation of complex heterocyclic frameworks. Beyond medicinal chemistry, the compound is increasingly utilised in the agrochemical industry as a high-purity intermediate for the synthesis of advanced fungicides and insecticides like metconazole and chlorfenapyr, supporting the transition towards more selective and environmentally sustainable crop protection solutions. We are a globally established Trimethylsulfoxonium Bromide intermediates supplier with >= 99% purity, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting Trimethylsulfoxonium Bromide COA/TDS/SDS region-specific regulatory support, reliable lead times, and worldwide supply chain capabilities.

Trimethylsulfoxonium Bromide (TMSOBR)

Trimethylsulfoxonium Bromide (CAS No: 25596-24-1) is a vital sulfoxonium salt that serves as an indispensable reagent in modern organic synthesis, particularly through the Corey-Chaykovsky reaction to facilitate the stereoselective construction of epoxides, cyclopropanes, and aziridines. In the global pharmaceutical sector, it functions as a critical synthetic building block for producing active pharmaceutical ingredients (APIs) such as methylcobalamin and various antiviral or antifungal agents, where its role in generating dimethylsulfoxonium methylide allows for the efficient formation of complex heterocyclic frameworks. Beyond medicinal chemistry, the compound is increasingly utilised in ...

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Chemical Properties & Specifications

Applications of Trimethylsulfoxonium Bromide (TMSOBR)

Organic Synthesis Reagent

A versatile sulfur ylide precursor primarily used for the generation of dimethyloxosulfonium methylide to facilitate epoxidation, cyclopropanation, and methylene transfer reactions

Pharmaceutical Intermediate

A critical building block utilized in the synthesis of various medicinal compounds, including the production of methylcobalamin and steroid hormones

Agrochemical Intermediate

An important organic intermediate employed in the production of herbicides, pesticides, and fungicidal thiazole derivatives

Industrial Chemical

A functionalized sulfoxonium salt used as a catalyst, phase-transfer catalyst, or reactant in the synthesis of heterocyclic compounds and fluorescent materials.

Have Questions About Trimethylsulfoxonium Bromide (TMSOBR)?
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Trimethylsulfoxonium Bromide (TMSOBR) is a sulfoxonium salt primarily used as a reagent in organic synthesis for methylene transfer reactions, such as the Corey-Chaykovsky reaction to prepare epoxides, and as an intermediate for fungicides and pharmaceuticals

This compound is widely utilized in the pharmaceutical, agrochemical, and chemical manufacturing industries for the production of herbicides, pesticides, steroid hormones, and fine chemicals

It is a stable crystalline powder soluble in water and methanol, typically used in liquid-phase organic synthesis and controlled laboratory environments

Standard specifications include CAS number 25596-24-1, high purity (typically ≥98%), and documentation such as COA, TDS, impurity reports, and regulatory compliance documents

Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time

The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.

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