Trimethyl Silyl Iodide

CAS Number: 16029-98-4

Molecular Formula: C3H9ISi

About Trimethyl Silyl Iodide

Iodotrimethylsilane CAS 16029-98-4 is a premier silylating agent and Lewis acid catalyst in the API intermediates market, essential for the regioselective deprotection of carbamates and the synthesis of complex antibiotics like Ceftazidime with a required pharma purity of 99%. Trimethylsilyl iodide serves as a high pur...

Trimethyl Silyl Iodide Specifications

CAS Number

16029-98-4

Molecular Formula

C3H9ISi

Molecular Weight

200.09 g/mol

IUPAC Name

iodo(trimethyl)silane

Canonical SMILES

C[Si](C)(C)I

InChI Key

CSRZQMIRAZTJOY-UHFFFAOYSA-N

PubChem CID

85247

CAS Number

16029-98-4

Molecular Formula

C3H9ISi

Molecular Weight

200.09 g/mol

IUPAC Name

iodo(trimethyl)silane

Canonical SMILES

C[Si](C)(C)I

InChI Key

CSRZQMIRAZTJOY-UHFFFAOYSA-N

PubChem CID

85247

Molecular Weight

200.09 g/mol

Physical appearance

Clear colorless to brown liquid

Synthetic Reagent and Silylating Agent

A multipurpose reagent and powerful silylating agent used for the dealkylation of ethers, esters, lactones, and carbamates, as well as for the introduction of trimethylsilyl groups to enhance the reactivity and stability of organic molecules

Pharmaceutical Intermediate

A critical building block utilized in the synthesis of complex active pharmaceutical ingredients, including cephalosporins such as ceftazidime, and as a selective deprotection agent for N-Cbz and Boc protecting groups

Reactive Ligand

A chemically reactive agent used as a ligand for surface etching and passivation of perovskite nanocrystals to improve the efficiency and stability of light-emitting diodes

Lewis Acid Catalyst

A versatile catalyst and hard-soft reagent employed in various organic transformations, such as Aza-Prins cyclizations for the synthesis of substituted piperidines and the regioselective hydroiodination of dienyl alcohols.