Trichloroacetic acid (TCA)

Trichloroacetic acid (TCA)

CAS Number
76-03-9
Molecular Formula
C2HCl3O2
CorrosiveCorrosive
Environmental HazardEnvironmental Hazard

About Trichloroacetic acid (TCA)

Trichloroacetic acid (TCA) is a potent halogenated organic acid and strong, water-soluble monocarboxylic acid (molecular formula CCl3COOH) produced via the chlorination of acetic acid, serving as a critical building block across dermatology, pharmaceuticals, chemical synthesis, and laboratory diagnostics. The global tr...

Synonyms

  • Varitox
  • Trikloreddiksyre
  • TkhVk
  • TCA solution
  • TkhV

Trichloroacetic acid (TCA) Specifications

CAS Number
76-03-9
Molecular Formula
C2HCl3O2
Molecular Weight
163.38 g/mol
IUPAC Name
2,2,2-trichloroacetic acid
Canonical SMILES
C(=O)(C(Cl)(Cl)Cl)O
InChI Key
YNJBWRMUSHSURL-UHFFFAOYSA-N
InChI
InChI=1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)
UNII Code
5V2JDO056X
ChEBI ID
CHEBI:30956
HMDB ID
HMDB0042048
DSSTox Substance ID
DTXSID1021378
EINECS Number
200-927-2
UN Number
1839
MDL Number
MFCD00004177
Molecular Weight
163.38 g/mol
XLogP3
1.3
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
0
Exact Mass
161.904212 Da
Monoisotopic Mass
161.904212 Da
Melting Point
135 to 136 °F
Boiling Point
385 to 387 °F at 760 mmHg
Flash Point
greater than 230 °F
GHS Hazard Statements
H314: Causes severe skin burns and eye damage H400: Very toxic to aquatic life H410: Very toxic to aquatic life with long lasting effects
Hazard Classes and Categories
Acute toxicity (Oral) - Category 5 Skin corrosion/irritation - Category 1A-1C Serious eye damage/eye irritation - Category 1 Germ cell mutagenicity - Category 2 Carcinogenicity - Category 2 Reproductive toxicity - Category 2 Specific target organ toxicity - Single exposure - Category 2 (respiratory system), Category 3 (narcotic effects)

Cosmetics and Dermatology

A chemical peel agent used to treat skin conditions such as acne scars, wrinkles, warts, and hyperpigmentation

Biochemistry and Clinical Chemistry

A highly effective agent used to denature and precipitate proteins and nucleic acids from biological fluids for sample preparation and purification

Organic Synthesis

An acid catalyst and reagent utilized in reactions like esterification, hydrolysis, and the selective deprotection of acid-labile groups

Material Science and Polymer Chemistry

A surface modification and polymer degradation agent used to treat polymer surfaces or break down complex polymer chains through hydrolysis

  1. Varitox
  2. Trikloreddiksyre
  3. TkhVk
  4. TCA solution
  5. TkhV

Trichloroacetic acid (TCA) FAQs

Minimum Order Quantity

25 kg (pilot) · 1 MT (commercial)

Lead Time

3 – 5 weeks ex-works

Incoterms

FOB · CIF

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

Regional Availability

India · EU · Middle East · Southeast Asia

Documentation

SDS · COA · TDS available on request

Compliance & Quality

REACH registered*

GHS/SDS available

ISO 9001:2015 site*

RoHS compliant*

Global sourcing network

Consistent quality & reliability

End-to-end technical support

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