TRIAMCINOLONE-9,11B-EPOXIDE (5TR)

CAS Number: 215095-77-5

Molecular Formula: C21H26O6

About TRIAMCINOLONE-9,11B-EPOXIDE (5TR)

Triamcinolone-9,11b-epoxide CAS 215095-77-5 functions as a critical corticosteroid intermediate in the API intermediates market, primarily utilised for the high-efficiency synthesis of triamcinolone acetonide and other fluorinated glucocorticoids. As a high purity fine chemicals specialist, the triamcinolone epoxy (5TR...

TRIAMCINOLONE-9,11B-EPOXIDE (5TR) Specifications

CAS Number

215095-77-5

Molecular Formula

C21H26O6

Molecular Weight

374.43 g/mol

IUPAC Name

(9,16b)-9,11-Epoxy-16,17,21-trihydroxypregna-1,4-diene-3,20-dione

Canonical SMILES

[C@@]123[C@@]([H])(CCC4=CC(=O)C=C[C@]14C)[C@]1([H])C[C@@H](O)[C@](O)(C(CO)=O)[C@@]1(C)C[C@@H]2O3

InChI Key

MJJGOAZIKWEYHG-IHBGMWQBNA-N

PubChem CID

53486388.0

CAS Number

215095-77-5

Molecular Formula

C21H26O6

Molecular Weight

374.43 g/mol

IUPAC Name

(9,16b)-9,11-Epoxy-16,17,21-trihydroxypregna-1,4-diene-3,20-dione

Canonical SMILES

[C@@]123[C@@]([H])(CCC4=CC(=O)C=C[C@]14C)[C@]1([H])C[C@@H](O)[C@](O)(C(CO)=O)[C@@]1(C)C[C@@H]2O3

InChI Key

MJJGOAZIKWEYHG-IHBGMWQBNA-N

PubChem CID

53486388.0

Molecular Weight

374.43 g/mol

Physical appearance

White to almost white powder to crystal

Pharmaceutical Intermediate

An essential synthetic precursor and building block used in the production of highly potent corticosteroid drugs, including betamethasone, dexamethasone, mometasone, beclomethasone, and triamcinolone acetonide

Reference Standard

A high-purity analytical standard utilized in pharmaceutical research, quality control, and HPLC analysis for the identification and quantification of process-related impurities in steroid manufacturing

Chemical Synthesis Intermediate

A critical epoxide intermediate employed in regioselective chemical transformations to introduce 9-alpha-halo and 11-beta-hydroxy functionalities necessary for the biological activity of glucocorticoid agonists.